Results 101 to 110 of about 380,214 (349)

Sexuality in the 21st Century: Sexual Fluidity.

East Asian Archives of Psychiatry, 2019
Sexuality is a vital component of human life. Sexuality deals with procreation and pleasure. Sexual behaviours and orientations vary and may be related to mental health.
A. Ventriglio, D. Bhugra
semanticscholar   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Couette Flow of Two-Dimensional Foams

, 2010
We experimentally investigate flow of quasi two-dimensional disordered foams in Couette geometries, both for foams squeezed below a top plate and for freely floating foams. With the top-plate, the flows are strongly localized and rate dependent.
Aussillous P., B. P. Tighe, Dennin M., G. Katgert, Höhler R., Larson R. G., M. E. Möbius, M. van Hecke, Möbius M. E., Rodts S., Terriac E.   +10 more
core   +1 more source

Individual preferences, social mobility and electoral outcomes [PDF]

, 1990
This paper models data for the Netherlands in the 1970s on prestige of male's occupation, occupational prestige of the father and ‘left/right’ score of the political party he prefers.
Graaf, Nan Dirk de, Ultee, Wout
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Effect of Fe Amount on Microstructure and Fluidity of A356 Alloy [PDF]

Archives of Foundry Engineering
The most important factor affecting the production of quality parts with aluminum alloys is the quality of molten metal. One of the determining factors in molten metal quality is the minimization of trace impurity elements in the alloy.
M. Durmus, D. Dispinar, M. Gavgali, M. Colak   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Flotillin-mediated membrane fluidity controls peptidoglycan synthesis and MreB movement

bioRxiv, 2019
The bacterial plasma membrane is an important cellular compartment. In recent years it has become obvious that protein complexes and lipids are not uniformly distributed within membranes.
A. Zielińska, Abigail Savietto, A. de Sousa Borges, Joël R. Roelofsen, Alwin M. Hartman, Rinse de Boer, I. J. van der Klei, A. Hirsch, M. Bramkamp, D. Scheffers   +9 more
semanticscholar   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Spatial cooperativity in microchannel flows of soft jammed materials: A mesoscopic approach

, 2013
The flow of amorphous solids results from a combination of elastic deformation and local structural rearrangements, which induce non-local elastic deformations.
Barrat, Jean-Louis, Nicolas, Alexandre
core   +3 more sources