Results 121 to 130 of about 111,384 (304)

Sexual Fluidity: An Integrative Review

, 2018
Historically, sexuality had been considered a fundamental, biologically determined characteristic of humans. Lately, better protection of human rights and recognition of non-traditional relationships have been leading to acceptance towards gay ...
Hunt, Steve, Hunt, Elena
core   +1 more source

Membrane fluidity and hypertension [PDF]

American Journal of Hypertension, 2003
Kazushi, Tsuda, Ichiro, Nishio
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

ICYGMB 2007: 23rd International Conference on Yeast Genetics and Molecular Biology [PDF]

, 2007
Adaptation of yeasts to changing environments during growth, fermentation and bioprocessing requires rapid modulation of membrane fluidity. We studied fluidity modulation in S.
Learmonth, Robert, Butcher, Brett A.
core  

The conceptualisation of sexual fluidity.

, 2019
The research dossier consists of three research reports: a literature review and two qualitative studies; an Interpretative Phenomenological Analysis (IPA) and a Foucauldian Discourse Analysis (FDA).
Patursson, Lisa
core   +1 more source

Determination of composition and fluidity of an alloy for impregnating hard alloys on the basis of titanium carbide

Metalurgija, 2016
In this paper optimum compositions of a metal bond of Cr – Ni - Co system are determined by mathematical planning methods. As a response function, value of bending strength at a temperature of 800 °C was used.
A. Z. Issagulov, Sv. S. Kvon, V. Yu. Kulikov, Т. S. Filippova, G. K. Kоshebayeva, I. I. Yerakhtina   +5 more
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Designing Gender Inclusivity and Equality

, 2013
In consideration of the labels and definitions of gender identities, and the differences in experience of stasis or fluidity of gender, this paper describes a role for design in the political activities of gender diversity inclusion and equality as a ...
Hilton, Kevin
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source