Results 131 to 140 of about 380,214 (349)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
ON THE POSSIBLE FORMATION MECHANISM OF THE OPEN FRACTURING IN SEDIMENTARY BASINS
Геодинамика и тектонофизикаThe paper shows that the formation of orthogonal systems of open macrofractures (cleavages) of sedimentary basins can occur at the stage of diagenesis during the first hundreds of years for a small range of shelf depths (up to 100 m) during sedimentation.
Yu. L. Rebetsky
doaj +1 more source
Memory and music in Mikhail Bulgakov's The Master and Margarita: Defying the regime [PDF]
Logos et Littera: Interdisciplinary Approaches to Text, 2017 Mikhail Bulgakov’s The Master and Margarita reveals intricate intersections, which are negotiated via memory and writing. Witnessing the collapse of the Russian Empire and the emergence of the Soviet Union, Bulgakov devises multiple ways to engage not ...
Nataliya Shpylova-Saeed +1 more
doaj
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Impact of attractive interactions on the rheology of dense athermal particles
, 2014 Using numerical simulations, the rheological response of an athermal assembly of soft particles with tunable attractive interactions is studied in the vicinity of jamming.
Chaudhuri, Pinaki +2 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
FRAGMENTED IDENTITIES IN ANDRIC’S SHORT STORIES [PDF]
Hum, 2012 Through the title topic authors analyze the issue of identity in Andric’s paradigmatic short stories. Fragmentation of identities is manifested in relation to the other in searching for completeness.
Branka Brlenić-Vujić +1 more
doaj
Flexible Lipid Bilayers in Implicit Solvent
, 2005 A minimalist simulation model for lipid bilayers is presented. Each lipid is represented by a flexible chain of beads in implicit solvent. The hydrophobic effect is mimicked through an intermolecular pair potential localized at the ``water''/hydrocarbon ...
A. Ben-Shaul +14 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source