Results 81 to 90 of about 368,855 (337)

The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers. [PDF]

, 2011
Encapsulation of drugs within nanocarriers that selectively target malignant cells promises to mitigate side effects of conventional chemotherapy and to enable delivery of the unique drug combinations needed for personalized medicine.
Ashley, Carlee E, Brinker, C Jeffrey, Brown, Page A, Carnes, Eric C, Carroll, Nick J, Carter, Mark B, Chackerian, Bryce, Dunphy, Darren R, Durfee, Paul N, Evans, Deborah G, Hanna, Tracey N, Jiang, Xingmao, Liu, Juewen, Padilla, David, Parikh, Atul N, Peabody, David S, Petsev, Dimiter N, Phillips, Brandy, Phillips, Genevieve K, Wharton, Walker, Willman, Cheryl L   +20 more
core   +2 more sources

Flotillin-mediated membrane fluidity controls peptidoglycan synthesis and MreB movement

bioRxiv, 2019
The bacterial plasma membrane is an important cellular compartment. In recent years it has become obvious that protein complexes and lipids are not uniformly distributed within membranes.
A. Zielińska, Abigail Savietto, A. de Sousa Borges, Joël R. Roelofsen, Alwin M. Hartman, Rinse de Boer, I. J. van der Klei, A. Hirsch, M. Bramkamp, D. Scheffers   +9 more
semanticscholar   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Modelling complexity of gender as an agent of change [PDF]

, 2006
Social inclusion continues to develop as a key issue in responsible design practices. To date, we have witnessed change in the development of inclusivity for the aged, and the physically and mentally challenged, but little more than exploration by ...
Hilton, Kevin
core  

Fluidisation and plastic activity in a model soft-glassy material flowing in micro-channels with rough walls

, 2016
By means of mesoscopic numerical simulations of a model soft-glassy material, we investigate the role of boundary roughness on the flow behaviour of the material, probing the bulk/wall and global/local rheologies.
Bernaschi, Massimo, Lulli, Matteo, Sbragaglia, Mauro, Scagliarini, Andrea   +3 more
core   +1 more source

Supplementation of iron alone and combined with vitamins improves haematological status, erythrocyte membrane fluidity and oxidative stress in anaemic pregnant women [PDF]

, 2010
Pregnancy is a condition exhibiting increased susceptibility to oxidative stress, and Fe plays a central role in generating harmful oxygen species. The objective of the present study is to investigate the changes in haematological status, oxidative ...
Aiguo, M., Chen Jiang, D., Kok, F.J., Schouten, E.G., Xia Han, Xiu, Yang, Fang, Ye Sun, Yong, Zhi Zhang, Feng   +7 more
core   +2 more sources

Sexuality in the 21st Century: Sexual Fluidity.

East Asian Archives of Psychiatry, 2019
Sexuality is a vital component of human life. Sexuality deals with procreation and pleasure. Sexual behaviours and orientations vary and may be related to mental health.
A. Ventriglio, D. Bhugra
semanticscholar   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

FOAM GYPSUM PRODUCTS BASED ON LOCAL BINDERS

Вестник Дагестанского государственного технического университета: Технические науки, 2019
Objectives. The problems of production of porous gypsum products on a local gypsum binder in the Karachay-Cherkess Republic are considered. Method.
A. S. Bagdasarov, A. I. Nesterenko, A. Yu. Pupkova   +2 more
doaj   +1 more source