Results 131 to 140 of about 51,811 (263)

Lineal Energy or Linear Energy Transfer? A comparative study using an SOI microdosimeter and a Timepix3 detector in a Helium‐ion pristine peak

Precision Radiation Oncology, EarlyView.
Yasmin Hamad, Sandra Barna, Tim Gehrke, Andrea Mairani   +3 more
wiley   +1 more source

Methionine Regulates Antitumour Function of CD8+ T Cells Through Polyamine Synthesis

Immunology, EarlyView.
Methionine restriction in vitro enhances CD8+ T cell effector function by suppressing polyamine synthesis and progressively induces the co‐expression of PD‐1 and TIM‐3. Consistently, sustained dietary methionine restriction diminishes the efficacy of adoptive T cell therapy (ACT) and promotes the expression of terminal exhaustion‐associated markers ...
Tian Zhao, Gillian A. Carleton, Sam Preshaw, Sarah MacPherson, Madison Shiyuk, Joseph Monaghan, Jun Han, Oro Uchenunu, Robert Rottapel, Ralph J. DeBerardinis, Kelly M. Stewart, Bo‐Hyun Kim, Juan Ausió, David R. Goodlett, Helena Pětrošová, Kyle D. Duncan, Julian J. Lum   +16 more
wiley   +1 more source

A posttranslational proteomic survey of a single anatomically preserved human 20‐week postconception brain

Journal of Anatomy, EarlyView.
A well‐preserved 20 post‐conception week human brain was obtained and finely dissected into 18 anatomically distinct regions, including the pia mater. Each region underwent in‐depth proteomic analysis, encompassing both total protein content and post‐translational modifications.
S. Bandiera, H. Bogetofte, P. Jensen, R. Hussain, S. A. Nischal, L. Rihova, G. J. Clowry, M. R. Larsen, Z. Molnár, B. C. Carlyle   +9 more
wiley   +1 more source

Benchmarking of the efficiency of the NaI(Tl) detector using FLUKA, MCNP, and experimental measurements at multiple source distances

Nuclear Analysis
Accurate calibration of NaI(Tl) scintillation detectors is essential for reliable gamma-ray spectrometry in nuclear safeguards and environmental radiation monitoring.
Zeenat Ullah, Abdelhamid Jalil, Xianpeng Yin, Yingming Sang, Javed Hussain, Muhammad Shoaib, Ghulam Hussan, Da Chen   +7 more
doaj   +1 more source

Saffron aqueous extract effects on paraquat and glyphosate concentration in common carp (Cyprinus carpio) tissues

Agricultural &Environmental Letters, Volume 11, Issue 2, December 2026.
Reduced bioaccumulation of PQ and GLY by saffron extract in Common carp (Cyprinus carpio) tissues Abstract Herbicides such as paraquat (PQ) and glyphosate (GLY) pose ecological and public health risks because of their persistence, bioaccumulation, and toxicity to aquatic organisms. This study evaluated whether aqueous saffron extract (Crocus sativus L.)
Hossein Hammami, Javad Kharkan
wiley   +1 more source

Dorso‐Ventral and Night‐Day Regulation of Extracellular K+ Dynamics in Mouse Hippocampal Astrocytes

Glia, Volume 74, Issue 9, September 2026.
Hippocampal astrocytic K+ buffering varies by region and time. Ventral astrocytes show faster K+ accumulation due to reduced Kir4.1 function. Such regional divergence is modulated by circadian shifts in Kir4.1 and gap junction coupling. ABSTRACT Astrocytes regulate extracellular potassium (K+) through multiple mechanisms operating across distinct ...
Nariman Kiani, Kabeer Abubakar, Tin Luka Petanjek, Monique Esclapez, Anton Ivanov, Christophe Bernard   +5 more
wiley   +1 more source

Integrative Phytochemical, Antioxidant, and NLRP3‐Linked and Anti‐Inflammatory Evaluation of Salvia balansae (Aurès Chemotype): Insights Into Its Safety and Therapeutic Potential

ChemistryOpen, Volume 15, Issue 9, September 2026.
An endemic Aurès chemotype of Salvia balansae emerges as a rich source of luteolin, rosmarinic acid, and other polyphenols with potent antioxidant and NLRP3‐linked anti‐inflammatory activities. Protection against experimental inflammation, favorable enzyme‐modulating properties, and a wide safety margin highlight its promise as a pharmaceutical and ...
Khadra Afaf Bendrihem, Messaoud Hachemi, Mohamed Aimene Mihoubi, Fares Mohamed Amine, Majid Sharifi‐Rad, Dalal Houhou, Rahma Guemmaz, Khaled Kherraz, Azzeddine Zeraib, Assia Abdelmalek, Aicha Mouane, Nour Elhouda Ayeb, Chawki Bensuici, Maria Chikha, Kamel Nagaz, Ayomide Victor Atoki, Mohammed Messaoudi   +16 more
wiley   +1 more source

Development of the FLUKA Monte Carlo code and of its scientific and technological applications [PDF]

, 2002
The basic features of the FLUKA Monte Carlo code are reviewed, giving some detail about the modeling of hadronic interactions. At present, also in the framework of an INFN project, FLUKA is being adopted for different applications in the field of ...
G. Battistoni, OTTOLENGHI, ANDREA DAVIDE, A. Ferrari, M. Biaggi, P. Sala, BALLARINI, FRANCESCA   +5 more
core  

Multimerization of a rationally designed nanobody for enhanced avidity toward Aβ42 oligomers

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Alzheimer's disease affects tens of millions of people worldwide and is associated with the self‐assembly of the Aβ42 peptide into amyloid aggregates. Among the species formed during this process, soluble oligomeric intermediates are the most closely linked to neurotoxicity and are therefore an attractive target for both therapeutic and ...
Magdalena Nowinska, Elijah Suh, Casey Mogilevsky, Michele Vendruscolo   +3 more
wiley   +1 more source

Glove Reuse Limits in Hair Dyeing: Permeation of p‐Phenylenediamine and Aminophenols Through Natural Rubber Latex and Neoprene After Repeated Washing

Contact Dermatitis, Volume 95, Issue 3, Page 309-317, September 2026.
Disposable glove reuse reduced chemical protection during repeated hair‐dye exposure. Under ASTM F739 testing, natural‐rubber‐latex deteriorated rapidly after one reuse, whereas neoprene performed better initially but also declined over repeated cycles. Wash type had no significant effect. These findings support single‐use only and discourage the reuse
Pei‐Ting Jian, Yu‐Wen Lin
wiley   +1 more source