Results 41 to 50 of about 262,034 (273)

Lensless Miniature Portable Fluorometer for Measurement of Chlorophyll and CDOM in Water Using Fluorescence Contact Imaging

open access: yesIEEE Photonics Journal, 2014
We report on the design, fabrication, and verification of a proof-of-concept miniature fluorometer, which is designed to measure chlorophyll and colored dissolved organic matter (CDOM) concentration in aquatic environment.
Lior Blockstein, Orly Yadid-Pecht
doaj   +1 more source

Positive feedback loop between MAPK and aquaporin 7 regulates autophagy and apoptosis induced by palmitate in RIN‐m5f cells

open access: yesFEBS Open Bio, EarlyView.
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang   +5 more
wiley   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

open access: yesFEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu   +6 more
wiley   +1 more source

Effect of 2% fluorescein on Scheimpflug central corneal thickness measurements [PDF]

open access: yesInternational Journal of Ophthalmology, 2016
AIM: To assess central corneal thickness (CCT) changes measured with Scheimpflug device following instillation of 2% fluorescein in normal subjects. METHODS: This was a prospective randomized study of 60 hospital volunteers.
Stella Briggs, Marwa Bin Moammar
doaj   +1 more source

Ocular surface staining: Current concepts and techniques

open access: yesIndian Journal of Ophthalmology, 2023
The health of the ocular surface is vital for clear vision and comfort. Various factors can adversely influence the ocular surface and tear film homeostasis, and these include procedures like cataract and corneal refractive surgery.
Sanjeev P Srinivas, Srinivas K Rao
doaj   +1 more source

Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis

open access: yesAdvanced Biology, EarlyView.
Transmembrane signaling is the hallmark of living cells and is among the highest challenges for the design of synthetic cells. Herein, an artificial receptor based on the chemistry of self‐immolative linkers is used to communicate information across the lipid bilayer, for transmembrane activation of enzymatic activity. Abstract The design of artificial,
Ane Bretschneider Søgaard   +7 more
wiley   +1 more source

New synthetic strategies for xanthene-dye-appended cyclodextrins

open access: yesBeilstein Journal of Organic Chemistry, 2016
Xanthene dyes can be appended to cyclodextrins via an ester or amide bridge in order to switch the fluorescence on or off. This is made possible through the formation of nonfluorescent lactones or lactams as the fluorophore can reversibly cyclize.
Milo Malanga   +5 more
doaj   +1 more source

Light‐Triggered Protease‐Mediated Release of Actin‐Bound Cargo from Synthetic Cells

open access: yesAdvanced Biology, EarlyView.
TEV Prtoease‐mediated Releasable Actin‐binding Protein (TRAP) is a protein‐based platform consisting of a cargo tightly bound to reconstituted actin networks in synthetic cells which can be proteolyticly released from the bound actin, followed by its secretion through membrane translocation mediated by a cell‐penetrating peptide.
Mousumi Akter   +3 more
wiley   +1 more source

Fluorophores Use in Pituitary Surgery: A Pharmacokinetics and Pharmacodynamics Appraisal

open access: yesBrain Sciences, 2021
(1) Background: Despite many surgical and technological advances, pituitary adenoma surgery is still burdened by non-negligible rates of incomplete tumor resection, mainly due to difficulties in differentiating pathology from normal pituitary tissue ...
Daniele Bongetta   +9 more
doaj   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

open access: yesAdvanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim   +3 more
wiley   +1 more source

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