Results 81 to 90 of about 481,368 (398)

Polycations as Aptamer-Binding Modulators for Sensitive Fluorescence Anisotropy Assay of Aflatoxin B1

open access: yesSensors
Fluorescence induced by the excitation of a fluorophore with plane-polarized light has a different polarization depending on the size of the fluorophore-containing reagent and the rate of its rotation.
Alexey V. Samokhvalov   +4 more
doaj   +1 more source

New synthetic strategies for xanthene-dye-appended cyclodextrins

open access: yesBeilstein Journal of Organic Chemistry, 2016
Xanthene dyes can be appended to cyclodextrins via an ester or amide bridge in order to switch the fluorescence on or off. This is made possible through the formation of nonfluorescent lactones or lactams as the fluorophore can reversibly cyclize.
Milo Malanga   +5 more
doaj   +1 more source

Staining and peeling of the internal limiting membrane using a fluorescent dye (Rhodamine 6 G) [PDF]

open access: yes, 2008
Aim: To assess whether low concentrations of a fluorescent dye such as Rhodamine 6G would help the unaided human eye visualise the vitreous and the internal limiting membrane (ILM) under standard halogen illumination.Material/methods: The UV/Vis ...
Haritoglou, Christos   +6 more
core   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

open access: yesAdvanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim   +8 more
wiley   +1 more source

Quantitative photoluminescence of broad band absorbing melanins: A procedure to correct for inner filter and re-absorption effects

open access: yes, 2004
We report methods for correcting the photoluminescence emission and excitation spectra of highly absorbing samples for re-absorption and inner filter effects.
Forest   +19 more
core   +1 more source

Transient Stiffness Patterning in Hydrogels Driven by Dissipative Mechanochemical Coupling

open access: yesAdvanced Functional Materials, EarlyView.
Force‐induced disulfide bond rupture in a polymer‐based hydrogel, coupled with chemical or electrochemical reoxidation, leads to the transient modulation of the hydrogel's stiffness properties. High spatiotemporal control is achieved by this dissipative process, enabling the development of out‐of‐equilibrium stiffness patterns and transient, dose ...
Roberto Baretta   +2 more
wiley   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

open access: yesAdvanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh   +3 more
wiley   +1 more source

Use of a distant reporter group as evidence for a conformational change in a sensory receptor [PDF]

open access: yes, 1977
A highly sensitive method for demonstrating ligand-induced conformational changes in protein molecules in solution is described. The method utilizes an environmentally sensitive reporter group that is known to be distant from the active site.
Hartig, P. R.   +2 more
core  

Conformational Dynamics of the Plug Domain of the SecYEG Protein-conducting Channel [PDF]

open access: yes, 2011
The central pore of the SecYEG preprotein-conducting channel is closed at the periplasmic face of the membrane by a plug domain. To study its conformational dynamics, the plug was labeled site-specifically with an environment-sensitive fluorophore.
Arkowitz   +44 more
core   +2 more sources

Rotating Liquid Marble Microreactors for Enhanced Enzymatic Reactions

open access: yesAdvanced Functional Materials, EarlyView.
Dynamic magnetic liquid marbles (LMs), stabilized by hydrophobic magnetic proteinaceous colloidosomes, function as effective microreactors for enzymatic processes. Precise magnetic manipulation allows for the rotation of these LMs, enhancing the efficiency of the enzymatic cascade reaction both at the air/water interface and within biphasic enzyme ...
Weijie Jiang   +5 more
wiley   +1 more source

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