Results 181 to 190 of about 13,314 (255)

Ultrathin Multi‐Doped Molybdenum Oxide Nanodots as a Tunable Selective Biocatalyst

open access: yesAdvanced Science, EarlyView.
This paper presents an advanced multi‐doped molybdenum oxide nanodots with tunable ammonium and proton doping, exhibiting strong ROS generation. The material demonstrates ultrafast and complete dye degradation and unique selective toxicity toward cancer cells, highlighting its promising potential for cancer therapy applications.
Bao Yue Zhang   +19 more
wiley   +1 more source

Physiological pH Transition‐Driven Protein Corona Dynamics Regulate Cellular Uptake and Inflammatory Responses of Silica Nanoparticles

open access: yesAdvanced Science, EarlyView.
Physiological pH transitions modulate protein corona dynamics on nanoparticles, altering their cellular uptake and inflammatory responses. Acidic pHs enhance protein adsorption, induce structural changes, and promote cellular uptake. Simultaneously, inflammatory responses are reduced due to altered protein composition, including decreased ...
Yuting Ge   +7 more
wiley   +1 more source

A Nanomodulator Enhances Radiotherapy‐Induced In Situ Cancer Vaccine by Promoting Antigen‐Presenting of Tumor‐Associated Macrophage

open access: yesAdvanced Science, EarlyView.
A nanomodulator (Ft‐E64/Hf@Lipo) is developed, combining radiosensitizer hafnium (Hf) and the cysteine protease inhibitor E64, which cooperatively reinvigorated the antigen presentation of TAMs. Ft‐E64/Hf@Lipo sensitized‐RT generated abundant tumor neoantigens, and then E64/antigens, along with the apoptotic tumor cells, trafficked to TAMs via ...
Xiu Zhao   +9 more
wiley   +1 more source

FOXQ1 Regulates Brain Endothelial Mitochondrial Function by Orchestrating Calcium Signaling and Cristae Morphology

open access: yesAdvanced Science, EarlyView.
FOXQ1 emerges as a master transcriptional regulator of brain endothelial metabolism, orchestrating mitochondrial function through dual control of calcium signaling and cristae organization. This study reveals that brain endothelial cells rely on oxidative phosphorylation rather than glycolysis alone, challenging the current metabolic paradigm and ...
Wenzheng Zou   +8 more
wiley   +1 more source

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