Results 61 to 70 of about 81,185 (328)

New fluorescent perylene bisimide indicators—a platform for broadband pH optodes [PDF]

open access: yes, 2011
Asymmetric perylene bisimide (PBI) dyes are prepared and are shown to be suitable for the preparation of fluorescence chemosensors for pH. They carry one amino-functional substituent which introduces pH sensitivity via photoinduced electron transfer (PET)
A Rademacher   +56 more
core   +2 more sources

Self‐Feeding of Engineered Tissues via Controlled Glucose Release Facilitates Survival and Vascularization of Living Implants

open access: yesAdvanced Functional Materials, EarlyView.
ABSTRACT Engineering living matter has great clinical potential to deliver functional replacement organs. However, clinical translation remains hampered by the current inability to maintain viability of clinically relevant‐sized constructs. During the pre‐vascular phase, implants rely on nutrient diffusion for survival, which is insufficient at ...
Melvin Gurian   +5 more
wiley   +1 more source

Gold Nanoclusters as Dual Agents for Engineering Tumor Vascular Leakiness and Performing Photothermal Therapy

open access: yesAdvanced Functional Materials, EarlyView.
Many cancer nanotherapeutics, while potent, suffer from the inability to escape from the tumor vasculature, especially in the absence of endothelial permeability. In this work, ultrasmall gold nanoclusters could engineer nanomaterials induced endothelial leakiness (NanoEL) and harness strong NIR induced photothermal characteristics to suppress tumor ...
Nengyi Ni   +8 more
wiley   +1 more source

Fluorescent Polymeric Nanofibers as Ratiometric Multiplexed Skin Sensors of pH and Oxygen

open access: yesAdvanced Healthcare Materials, EarlyView.
Fluorescent polymeric nanofibers and nanorods are produced as ratiometric sensors of two important physiological parameters: pH and oxygen. They operate by dual Forster resonance energy transfer from large number of energy donor dyes to limited number of two distinct energy acceptors, enabling simultaneous sensing of pH and oxygen.
Rémi Pelletier   +2 more
wiley   +1 more source

Porous Coatings by Vapor Sublimation and Deposition for Molecular Channeling and Filtration in an Interstitial Fluid Microfiltration Device

open access: yesAdvanced Healthcare Materials, EarlyView.
A vapor‐based porous coating applied within nitinol tubes demonstrated complete suppression of cellular and tissue ingrowth, overcoming a major limitation of implantable interstitial fluid collection devices. Molecular channeling and diffusion are analyzed with probe molecules, showing reliable transport in vitro and in vivo. The coating also achieved >
Yu‐Ming Chang   +8 more
wiley   +1 more source

A Sacrificial 3D Printed Vessel‐on‐Chip Demonstrates a Versatile Approach to Model Granulation Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel method that combines 3D printing and organ‐on‐chip technology enables the creation of hollow channels lined with endothelial cells through a fibroblast‐populated connective tissue matrix. The model supports stable metabolic culture conditions, angiogenic sprouting, and immune cell migration, thereby demonstrating an easy and versatile method to
Jonas Jäger   +7 more
wiley   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

open access: yesAdvanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen   +9 more
wiley   +1 more source

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