Results 91 to 100 of about 2,158,256 (257)

Analysis of initial chlorophyll fluorescence induction kinetics in chloroplasts in terms of rate constants of donor side quenching release and electron trapping in photosystem II [PDF]

, 2008
The fluorescence induction F(t) of dark-adapted chloroplasts has been studied in multi-turnover 1 s light flashes (MTFs). A theoretical expression for the initial fluorescence rise is derived from a set of rate equations that describes the sequence of ...
Vredenberg, W.J.
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Eco-friendly synthesis of magnetic activated carbon from used water filter cartridges for efficient methylene blue adsorption

Cleaner Water
Using activated carbon (AC) derived from used water filter cartridges (UWFC), we developed a waste-to-resource method to remove dyes from water. Mild reactivation at 400°C for 1 h produced AC-UWFC, which was subsequently transformed into magnetic ...
Dilip D. Anuse, Suryakant A. Patil, Ashwini A. Chorumale, Akanksha G. Kolekar, Prachi P. Bote, Laxman S. Walekar, Mukund G. Mali, Samadhan P. Pawar   +7 more
doaj   +1 more source

Identification of single-point mutations in mycobacterial 16S rRNA sequences by confocal single-molecule fluorescence spectroscopy [PDF]

, 2006
Marme N, Friedrich A, Müller M, et al. Identification of single-point mutations in mycobacterial 16S rRNA sequences by confocal single-molecule fluorescence spectroscopy. Nucleic Acids Research.
Friedrich, Achim, Sauer, Markus, Nolte, Oliver, Wolfrum, Jürgen, Marme, Nicole, Knemeyer, Jens-Peter, Müller, Matthias, Hoheisel, Jörg D.   +7 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

On the Possibility of Fluorescent Capture Immunoassays on a Contact Lens

Biosensors
Blood samples and testing are routine in healthcare. Presently, there is a growing interest in using tear samples in place of blood. Tear samples can be obtained non-invasively and collection does not require the skills of a trained phlebotomist.
Kundan Sivashanmugan, E. Albert Reece, Joseph R. Lakowicz   +2 more
doaj   +1 more source

Modelling fluorescence quenching in systems with restricted diffusion: applications to oligonucleotides and polypeptides [PDF]

, 2004
The objectives of the present thesis are 1) to systematically develop a series of models and theoretical expressions for the diffusion-controlled reaction, which can be used to analyze the time-resolved fluorescence data in systems where the diffusion is
Wang, Xiaojuan
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Identification of oil contamination in process water using fluorescence excitation emission matrix (FEEM) and parallel factor analysis (PARAFAC)

Water Science and Technology
Fuel oil is widely used within Eskom, a power generation company in South Africa. Eskom's coal-fired power stations use up to 30,000 L of fuel oil per hour during a cold start-up, a consequence of which results in oil leaks to the dams. Oil contamination
Heena Madhav, Adam Gilmore
doaj   +1 more source

Interaction of apolipoprotein A-I in three different conformations with palmitoyl oleoyl phosphatidylcholine vesicles

Journal of Lipid Research, 2002
Interactions of apolipoprotein A-I (apoA-I) with cell membranes appear to be important in the initial steps of reverse cholesterol transport. The objective of this work was to examine the effect of three distinct conformations of apoA-I (lipid-free and ...
M. Alejandra Tricerri, Susana A. Sanchez, Cristina Arnulphi, Diane M. Durbin, Enrico Gratton, Ana Jonas   +5 more
doaj   +1 more source