Results 181 to 190 of about 2,736,752 (297)

Near-Infrared Imaging Using a Cathepsin-Targeted, Quenched Activity-Based Probe Identifies Naturally Occurring Canine Appendicular Osteosarcoma. [PDF]

Clin Cancer Res
Massie AM, Bradley CW, Mai W, DiBona J, Dunlap A, Huck J, Griffin M, Flesner B, Drobatz KJ, Singhal S, Holt D.   +10 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Monitoring Macrophage Polarization with Gene Expression Reporters and Bioluminescence Phasor Analysis

Chemical & Biomedical Imaging
Giulia Tedeschi, Mariana X. Navarro, Lorenzo Scipioni, Tanvi K. Sondhi, Jennifer A. Prescher, Michelle A. Digman   +5 more
doaj   +1 more source

Specific Lipid Peroxidation Products in Erythrocytes and Their Relationship to the Pathogenesis of Alzheimer's Disease. [PDF]

J Cell Mol Med
Martináková L, Chmátalová Z, Veverová K, Jurášová V, Katonová A, Laczó M, Laczó J, Vyhnálek M, Hort J, Skoumalová A.   +9 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

A novel room-temperature CQD fluorescent nanosensor for the first derivatization-free spectrofluorimetric determination of dalfampridine: application to biological fluids and content uniformity testing. [PDF]

RSC Adv
Elattar RH, Alossaimi MA, Abbas AEF, Khan AA, Rajab BS, Ghaith MM, Qasem AH, Magdy G.   +7 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Polyethyleneimine-Doped Carbon Quantum Dots as a Highly Sensitive Fluorescent Probe for HClO Sensing in Live Cell Imaging. [PDF]

Nanomaterials (Basel)
Yan Y, Jiang X, Wang X, Liu R, Hao C, Chen N, Wang W, Dai P.   +7 more
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Perylene Dye as a Measure of Dynamic Free Volume, Fragility, and Dynamic Glass Transition in Thin Polystyrene Films. [PDF]

Macromolecules
Yadav S, Roth CB.
europepmc   +1 more source