Results 31 to 40 of about 1,945,444 (315)

Time-Resolved Fluorescence Investigation of the Human Immunodeficiency Virus Type 1 Nucleocapsid Protein: Influence of the Binding of Nucleic Acids [PDF]

open access: yes, 1999
Depending on the HIV-1 isolate, MN or BH10, the nucleocapsid protein, NCp7, corresponds to a 55- or 71-amino acid length product, respectively. The MN NCp7 contains a single Trp residue at position 37 in the distal zinc finger motif, and the BH10 NCp7 ...
Piemont, Etienne   +13 more
core   +1 more source

Comprehensive correlation analysis for super-resolution dynamic fingerprinting of cellular compartments using the Zeiss Airyscan detector

open access: yesNature Communications, 2018
Different fluorescence fluctuation methods require specialized equipment and cannot be performed simultaneously. Here the authors present an implementation that includes many advanced fluorescence fluctuation techniques in a single analysis, by ...
L. Scipioni   +3 more
doaj   +1 more source

A fluctuation method to quantify in vivo fluorescence data [PDF]

open access: yes, 2006
Quantitative in vivo measurements are essential for developing a predictive understanding of cellular behavior. Here we present a technique that converts observed fluorescence intensities into numbers of molecules.
Y Uri Alon   +12 more
core   +1 more source

Picosecond fluorescence of intact and dissolved PSI-LHCI crystals [PDF]

open access: yes, 2008
Over the last years many crystal structures of photosynthetic pigment-protein complexes have been determined, and used extensively to model spectroscopic results obtained on the same proteins in solution. However, the crystal structure is not necessarily
Amerongen, H., van   +6 more
core   +1 more source

AO DIVER: Development of a three-dimensional adaptive optics system to advance the depth limits of multiphoton imaging

open access: yesAPL Photonics, 2020
Multiphoton microscopy (MPM) can non-invasively measure the dynamic biochemical properties deep in scattering biological samples and has the potential to accelerate clinical research with advances in deep tissue imaging.
S. Leemans   +3 more
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger   +7 more
wiley   +1 more source

Two-photon laser scanning fluorescence microscopy using photonic crystal fibre [PDF]

open access: yes, 2004
We report the application of a simple yet powerful modular pulse compression system, based on photonic crystal fibres which improves upon incumbent twophoton laser scanning fluorescence microscopy techniques.
McConnell, G., Riis, E.
core   +1 more source

Detection and Quantification of DNA by Fluorophore-Induced Plasmonic Current: A Novel Sensing Approach

open access: yesSensors
We report on the detection and quantification of aqueous DNA by a fluorophore-induced plasmonic current (FIPC) sensing method. FIPC is a mechanism described by our group in the literature where a fluorophore in close proximity to a plasmonically active ...
Daniel R. Pierce   +7 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall   +2 more
wiley   +1 more source

Identification of single-point mutations in mycobacterial 16S rRNA sequences by confocal single-molecule fluorescence spectroscopy [PDF]

open access: yes, 2006
Marme N, Friedrich A, Müller M, et al. Identification of single-point mutations in mycobacterial 16S rRNA sequences by confocal single-molecule fluorescence spectroscopy. Nucleic Acids Research.
Friedrich, Achim   +7 more
core   +2 more sources

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