Results 71 to 80 of about 2,746,497 (369)

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

Fluorescence antibunching microscopy

, 2011
Breaking the diffraction limit in microscopy by utilizing quantum properties of light has been the goal of intense research in the recent years. We propose a quantum superresolution technique based on non-classical emission statistics of fluorescent ...
D. Oron, M. Kendall, O. Schwartz
core   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Theoretical studies on triplet formations in nitrobenzoxadiazole (NBD) derivatives: The impact of donor group and heteroatom substitution

Results in Chemistry, 2021
Heavy-atom-free triplet photosensitizers (TPs) have attracted much interest due to the applications in triplet–triplet annihilation (TTA) and photodynamic therapy.
Chao Wang, Hui Juan Koh, Zhaochao Xu, Xiaogang Liu   +3 more
doaj  

Efficient nitrogen-vacancy centers' fluorescence excitation and collection from micrometer-sized diamond by a tapered optical fiber

, 2018
Efficiently excite nitrogen-vacancy (NV) centers in diamond and collect their fluorescence significantly benefit the fiber-optic-based NV sensors.
Arumugam, Sri Ranjini, Balasubramanian, Gopalakrishnan, Chang, Huan-Cheng, Du, Guanxiang, Duan, Dewen, Kavatamane, Vinaya Kumar, Tzeng, Yan-Kai   +6 more
core   +1 more source

Laser-controlled fluorescence in two-level systems [PDF]

, 2010
The ability to modify the character of fluorescent emission by a laser-controlled, optically nonlinear process has recently been shown theoretically feasible, and several possible applications have already been identified.
Allcock P., Andrews D. L., Andrews D. L., Andrews D. L., Andrews D. L., Andrews D. L., Andrews D. L., Andrews D. L., Andrews D. L., Andrews D. L., Andrews D. L., Andrews D. L., Anger P., Armoogum D. A., Asselberghs I., Beuerman E., Bradshaw D. S., Bradshaw D. S., Bradshaw D. S., Bradshaw D. S., Bradshaw D. S., Bradshaw D. S., Bradshaw D. S., Chernyak V., Craig D. P., David L. Andrews, David S. Bradshaw, Dávila Romero L. C., Dick B., Drobizhev M., Drobizhev M., Harke B., Hell S. W., Jagatap B. N., Jamie M. Leeder, Jenkins J. K., Juzelinas G., Kastrup L., Kirkpatrick S. M., Kleinman D. A., Klimov V. I., Kmetic M. A., Kondo A. E., Leasure S. C., Leegwater J. A., Marsh R. J., Meath W. J., Meath W. J., Mukamel S., Oudar J. L., Rahav S., Rigneault H., Spano F. C., Tran P., Valeur B., Venkatramani R., Willig K. I., Wortmann R., Yu Y.-J., Zhou L. C., Zrenner A.   +60 more
core   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

In Vivo Single-Cell Detection of Metabolic Oscillations in Stem Cells

Cell Reports, 2015
Through the use of bulk measurements in metabolic organs, the circadian clock was shown to play roles in organismal energy homeostasis. However, the relationship between metabolic and circadian oscillations has not been studied in vivo at a single-cell ...
Chiara Stringari, Hong Wang, Mikhail Geyfman, Viera Crosignani, Vivek Kumar, Joseph S. Takahashi, Bogi Andersen, Enrico Gratton   +7 more
doaj   +1 more source

The impact of the air-fluorescence yield on the reconstructed shower parameters of ultra-high energy cosmic rays [PDF]

, 2010
An accurate knowledge of the fluorescence yield and its dependence on atmospheric properties such as pressure, temperature or humidity is essential to obtain a reliable measurement of the primary energy of cosmic rays in experiments using the ...
Arqueros, F., Garcia-Pinto, D., Monasor, M., Vazquez, J. R.   +3 more
core   +3 more sources

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source