Tumor Microenvironment‐responsive Nanocatalyst for Targeted Chemodynamic Cancer Therapy
An Tumor microenvironment‐responsive nanocatalyst system composed of PLGA‐encapsulated Ca–Fe peroxide and polyarginine enables sustainable Fenton reaction in tumors. Low levels of H2O2 (50–100 µm) initiate the nanoparticle degradation, while polyarginine‐derived nitric oxide accelerates Fe3+ reduction, leading to self‐amplifying •OH generation for ...
Jun Ma, Jingjing Qiu, Shiren Wang
wiley +1 more source
Detection of nondisjunction and recombination in meiotic and postmeiotic cells from XYSxr [XY,Tp(Y)1Ct] mice using multicolor fluorescence in situ hybridization. [PDF]
Terry Ashley, Thomas Ried, David C. Ward
openalex +1 more source
Printing and Rerouting of Elastic and Protease Responsive Shape Memory Hydrogel Filaments
A biofabrication strategy, Rerouting of Free‐Floating Suspended Hydrogel Filaments (REFRESH), is developed enabling the printing of highly elastic, reconfigurable protease‐responsive hydrogel filaments with shape memory properties. The filaments can be manually braided, knotted, and rerouted to create intricate cell‐laden 3D architectures, expanding ...
Philip Lifwergren+10 more
wiley +1 more source
A fluorescence in situ hybridization (FISH) protocol was developed for nematodes in which nucleic acid probes are introduced within the organism via electroporation.
Casey L. Ruark-Seward+2 more
doaj
Single-molecule RNA Fluorescence in situ Hybridization (smFISH) in Caenorhabditis elegans
Single-molecule RNA fluorescence in situ hybridization (smFISH) is a technique to visualize individual RNA molecules using multiple fluorescently-labeled oligonucleotide probes specific to the target RNA (Raj et al., 2008; Lee et al., 2016a).
ChangHwan Lee+5 more
doaj +1 more source
NAV3-geenimerkkiainemenetelmän kehittämisprojekti [PDF]
Syöpä on hyvin yleinen geneettinen sairaus, johon sairastuu noin joka kolmas suomalainen elinikänsä aikana. NAV3-geeni on syöpään yhdistetty merkkiainegeeni, joka sijaitsee kromosomissa 12.
Hanhela, Maija, Joensuu, Maija
core
Synthetic Aspects and Characterization Needs in MOF Chemistry – from Discovery to Applications
Overcoming the challenges of phase discovery, synthesis optimization and scale‐up, characterization, and computational studies is essential to accelerate the large‐scale application of MOFs. Life‐cycle analyses and techno‐economic analyses need to be performed to realistically assess their potential for industrial relevance.
Bastian Achenbach+4 more
wiley +1 more source
A stem-less probe using spontaneous pairing between Cy3 and quencher for RNA detection
We herein report a stem-less probe for the detection of RNA that depends on pairing between Cy3 and nitro methyl red. In our design, two Cy3 residues and two nitro methyl red residues were introduced into an oligonucleotide. In the absence of the target,
Hiromu Kashida+2 more
doaj +1 more source
Fluorescence in situ hybridization for direct visualization of Gram-negative anaerobes in subgingival plaque samples [PDF]
H Gersdorf+2 more
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Covalent Organic Frameworks for Photocatalysis
This review provides an overview of recent advances in covalent organic frameworks (COFs) for photocatalysis, focusing on sustainable energy applications like water splitting, hydrogen peroxide generation, and CO2 and N2 reduction. It discusses design principles, structure‐function relationships, challenges in COF photocatalysis, and strategies to ...
Bikash Mishra+6 more
wiley +1 more source