Results 21 to 30 of about 232,156 (357)

HER 2 status in invasive breast cancer: Immunohistochemistry, fluorescence in-situ hybridization and chromogenic in-situ hybridization

Indian Journal of Pathology and Microbiology, 2012
Introduction : HER2/neu gene status in breast cancers can be evaluated by targeting protein and gene - immunohistochemistry (IHC) and fluorescence in-situ hybridization (FISH).
Hemlata S Shirsat, Sridhar Epari, Tanuja Shet, Rajani Bagal, Rohini Hawaldar, Sangeeta B Desai   +5 more
doaj   +1 more source

Detection of complete and partial chromosome gains and losses by comparative genomic in situ hybridization [PDF]

, 1993
Comparative genomic in situ hybridization (CGH) provides a new possibility for searching genomes for imbalanced genetic material. Labeled genomic test DNA, prepared from clinical or tumor specimens, is mixed with differently labeled control DNA prepared ...
Cremer, Thomas, Döhner, Hartmut, Joos, Stefan, Kovacs, Gyula, Lichter, Peter, Manoir, Stanislas du, Popp, Susanne, Robert-Nicoud, Michel, Schröck, Evelin, Speicher, Michael R.   +9 more
core   +1 more source

Fluorescence in situ hybridization improves the detection of 5q31 deletion in myelodysplastic syndromes without cytogenetic evidence of 5q-

Haematologica, 2008
Background More than 50% of patients with myelodysplastic syndromes present cytogenetic aberrations at diagnosis. Partial or complete deletion of the long arm of chromosome 5 is the most frequent abnormality.
Mar Mallo, Leonor Arenillas, Blanca Espinet, Marta Salido, Jesús Mª Hernández, Eva Lumbreras, Mónica del Rey, Eva Arranz, Soraya Ramiro, Patricia Font, Olga González, Mónica Renedo, José Cervera, Esperanza Such, Guillermo F. Sanz, Elisa Luño, Carmen Sanzo, Miriam González, María José Calasanz, José Mayans, Carlos García-Ballesteros, Victoria Amigo, Rosa Collado, Isabel Oliver, Félix Carbonell, Encarna Bureo, Andrés Insunza, Lucrecia Yañez, María José Muruzabal, Elena Gómez-Beltrán, Rafael Andreu, Pilar León, Valle Gómez, Ángeles Sanz, Natalia Casasola, Esperanza Moreno, Adrián Alegre, María Luisa Martín, Carmen Pedro, Sergi Serrano, Lourdes Florensa, Francesc Solé   +41 more
doaj   +1 more source

A simplified and rapid in situ hybridization protocol for planarians

BioTechniques, 2023
Whole-mount in situ hybridization is a critical technique for analyzing gene expression in planarians. While robust in situ protocols have been developed, these protocols are laborious, making them challenging to incorporate in an academic setting ...
Andrew J Gaetano, Ryan S King
doaj   +1 more source

Effect of native gastric mucus on in vivo hybridization therapies directed at Helicobacter pylori [PDF]

, 2015
Helicobacter pylori infects more than 50% of the worldwide population. It is mostly found deep in the gastric mucus lining of the stomach, being a major cause of peptic ulcers and gastric adenocarcinoma. To face the increasing resistance of H.
Azevedo, Nuno F, Braeckmans, Kevin, Dakwar, George, De Smedt, Stefaan, Figueiredo, Céu, Fontenete, Silvia, Forier, Katrien, Guimarães, Nuno, Leite, Marina, Remaut, Katrien, Santos, Rita, Stremersch, Stephan, Wengel, Jesper, Xiong, Ranhua   +13 more
core   +5 more sources

Rapid interphase and metaphase assessment of specific chromosomal changes in neuroectodermal tumor cells by in situ hybridization with chemically modified DNA probes [PDF]

, 1988
Repeated DNAs from the constitutive heterochromatin of human chromosomes 1 and 18 were used as probes in nonradioactive in situ hybridization experiments to define specific numerical and structural chromosome aberrations in three human glioma cell lines ...
A.H.N. Hopman, Atkin, Bigner, Brigati, Burns, Burns, Carine, Cavenee, Comings, Cooke, Cooke, Cremer, D. Tesin, Dale, Devilee, Devilee, Dudin, Durnam, Gosden, Hadlaczky, Hall, Henn, Higgins, Hopman, Hopman, Hopman, Hopman, Hopman, Joseph, Julien, Kinzler, Kohl, L. Manuelidis, Landegent, Landegent, Langer-Safer, Leary, Lund Jorgensen, Maniatis, Manuelidis, Manuelidis, Manuelidis, Manuelidis, Manuelidis, Manuelidis, Manuelidis, Manuelidis, Manuelidis, Manuelidis, McDermid, Müller, Müncke, Pinkel, Pinkel, Rappold, Schardin, Schwab, Shapiro, Siegel, T. Cremer, Therman, Trask, Willard, Wu, Yang   +64 more
core   +1 more source

Fluorescence in situ Hybridization (FISH) in the Microbiological Diagnostic of Deep Sternal Wound Infection (DSWI)

Infection and Drug Resistance, 2021
Nick Spindler,1 Annette Moter,2,3 Alexandra Wiessner,2,3 Tanja Gradistanac,4 Michael Borger,5 Arne C Rodloff,6 Stefan Langer,1 Judith Kikhney2,3 1Department of Orthopedic Surgery, Traumatology and Plastic Surgery, University Hospital Leipzig, Leipzig ...
Spindler N, Moter A, Wiessner A, Gradistanac T, Borger M, Rodloff AC, Langer S, Kikhney J   +7 more
doaj  

Multiplexed Single-Cell in situ RNA Profiling

Frontiers in Molecular Biosciences, 2021
The ability to quantify a large number of varied transcripts in single cells in their native spatial context is crucial to accelerate our understanding of health and disease.
Yu-Sheng Wang, Jia Guo
doaj   +1 more source

In Situ Hybridization Pada Kanker Payudara [PDF]

, 2014
Kesulitan yang dijumpai pada penanganan kanker payudara adalah terjadinya kekambuhan atau relaps. Deteksi status HER2 pada pasien merupakan salah satu upaya untuk mendeteksi terjadinya relaps dan juga untuk menentukan jenis terapi yang ada diberikan ...
Diah Witari, Ni Putu
core   +2 more sources

Detection of Individual RNA in Fixed Cells and Tissues by Chromogenic ISH

Bio-Protocol, 2020
Visualization of RNA molecules in situ helps to better understand the functions of expressed genes. Currently, most conventional in situ hybridization methods for visualization of individual RNAs are based on fluorescence detection.
Meng Jiang, Chen Lin, Rongqin Ke
doaj   +1 more source