Results 61 to 70 of about 4,840 (179)

Evaluation of a novel fluorescence polarization immunoassay for teicoplanin [PDF]

Antimicrobial Agents and Chemotherapy, 1993
A fluorescence polarization immunoassay (FPI) for teicoplanin that uses the TDx Instrument System (Abbott, Irving, Tex.) as an automated analyzer has been developed by Innotron of Oregon Inc. and was evaluated in patients with staphylococcal infections enrolled in a clinical trial of the antibiotic.
H, Cox, M, Whitby, G, Nimmo, G, Williams
openaire   +2 more sources

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, Volume 15, Issue 10, 13 March 2026.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

Sviluppo e valutazione di test diagnostici per la sierodiagnosi di brucellosi suina [PDF]

Veterinaria Italiana, 2012
Sono stati sviluppati una ELISA competitiva (c-ELISA), una ELISA indiretta (i-ELISA) e un test immunologico DELFIA (Dissociation-Enhanced Lanthanide Fluorescence Immunoassay) per la ricerca di anticorpi verso Brucella suis in sieri di maiale e cinghiale.
Tiziana Di Febo, Mirella Luciani, Ottavio Portanti, Barbara Bonfini, Rossella Lelli, Manuela Tittarelli   +5 more
doaj  

Direct Determination of a Small-Molecule Drug, Valproic Acid, by an Electrically-Detected Microcantilever Biosensor for Personalized Diagnostics

Biosensors, 2015
Direct, small-molecule determination of the antiepileptic drug, valproic acid, was investigated by a label-free, nanomechanical biosensor. Valproic acid has long been used as an antiepileptic medication, which is administered through therapeutic drug ...
Long-Sun Huang, Christian Gunawan, Yi-Kuang Yen, Kai-Fung Chang   +3 more
doaj   +1 more source

MARPLE: A Proximity‐Triggered CRISPR‐Cas13 Platform for Ultrasensitive Antibody Detection

Advanced Science, Volume 13, Issue 13, 3 March 2026.
MARPLE is a modular CRISPR‐Cas13 immunoassay that uses antibody‐induced proximity to trigger a toehold‐exchange reaction, releasing an RNA activator for Cas13. This one‐pot, isothermal architecture enables ultrasensitive (femtomolar) and highly specific detection of diverse antibodies, including therapeutic, pathogen‐specific, and cancer‐associated ...
Elena Spezzani, Luca Capelli, Denise Di Lena, Alejandro Chamorro‐Garcia, Rudy Ippodrino, Alessandro Porchetta, Alessandro Bertucci   +6 more
wiley   +1 more source

Estimation of Abbreviated Cyclosporine A Area under the Concentration-Time Curve in Allogenic Stem Cell Transplantation after Oral Administration

Journal of Transplantation, 2012
Measurements of Cyclosporine (CsA) systemic exposure permit its dose adjustment in allogenic stem cell transplantation recipients to prevent graft-versus-host disease.
Hanene ELjebari, Nadia Ben Fradj, Issam Salouage, Emna Gaies, Sameh Trabelsi, Nadia Jebabli, Mohamed Lakhal, Tarek Ben Othman, Anis Kouz   +8 more
doaj   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Aerogel Scaffolds: Breathing Life Into Tissue Repair and Companion Diagnostics

Aggregate, Volume 7, Issue 3, March 2026.
Aerogel scaffolds are emerging as multifunctional biomedical platforms that bridge regenerative engineering and molecular diagnostics. By integrating hierarchical porosity, tunable mechanics, and programmable surface chemistry, aerogels can simultaneously support tissue reconstruction and enable localized biomarker sampling and signal transduction ...
Hanlin Zhang, Ruixuan Zheng, Jing Lin, Jiawu Weng, Lexiang Zhang, Fangfu Ye   +5 more
wiley   +1 more source

CORRELATION OF BLOOD LEVELS OF CYCLOSPORINE AND IT'S METABOLITES AND LOCAL FACTORS WITH GINGIVAL OVERGROWTH IN IRANIAN RENAL ALLOGRAFT PATIENTS

Acta Medica Iranica, 1997
Forty renal allograft patients with three months under immunosuppression by cycloserine were examined for their gingival overgrowth and it's correlation with several parameters including the trough levels of blood cyclosporine and it's metabolites ...
M. Sahebjamee ., A.R. Dehpour ., M. Davarmanesh ., F. Azordegan ., M. Abbasi M. Lesan Pezeshki   +4 more
doaj