Results 41 to 50 of about 262,308 (303)

Identification of single-point mutations in mycobacterial 16S rRNA sequences by confocal single-molecule fluorescence spectroscopy

, 2006
Marme N, Friedrich A, Müller M, et al. Identification of single-point mutations in mycobacterial 16S rRNA sequences by confocal single-molecule fluorescence spectroscopy. Nucleic Acids Research.
Friedrich, Achim, Sauer, Markus, Nolte, Oliver, Wolfrum, Jürgen, Marme, Nicole, Knemeyer, Jens-Peter, Müller, Matthias, Hoheisel, Jörg D.   +7 more
core   +1 more source

A fluctuation method to quantify in vivo fluorescence data [PDF]

, 2006
Quantitative in vivo measurements are essential for developing a predictive understanding of cellular behavior. Here we present a technique that converts observed fluorescence intensities into numbers of molecules.
Y Uri Alon, Rosenfeld, Nitzan, Swain, Peter S, Alon, Uri, Theodore J. Perkins, Perkins, Theodore J, Michael B. Elowitz, Nitzan Rosenfeld, Peter S. Swain, Elowitz, Michael B, Swain, Peter S., Perkins, Theodore J., Elowitz, Michael B.   +12 more
core   +1 more source

Studies on glucose detection using graphene quantum dots prepared by hydrothermal method

Scientific Reports
The increasing number of diabetic patients is a critical global challenge and monitoring of glucose level in blood via simple technique is of great importance.
Swapnali P. Rajmane, Omkar S. Nille, G. B. Kolekar, Shivaji B. Sadale   +3 more
doaj   +1 more source

On the Possibility of Fluorescent Capture Immunoassays on a Contact Lens

Biosensors
Blood samples and testing are routine in healthcare. Presently, there is a growing interest in using tear samples in place of blood. Tear samples can be obtained non-invasively and collection does not require the skills of a trained phlebotomist.
Kundan Sivashanmugan, E. Albert Reece, Joseph R. Lakowicz   +2 more
doaj   +1 more source

Manipulating Propagation Constants of Silver Nanowire Plasmonic Waveguide Modes Using a Dielectric Multilayer Substrate

Applied Sciences, 2018
Experiments and numerical simulations demonstrate that when a silver nanowire is placed on a dielectric multilayer, but not the commonly used bare glass slide, the effective refractive index of the propagating surface plasmons along the silver nanowire ...
Yifeng Xiang, Junxue Chen, Douguo Zhang, Ruxue Wang, Yan Kuai, Fengya Lu, Xi Tang, Pei Wang, Hai Ming, Mary Rosenfeld, Ramachandram Badugu, Joseph R. Lakowicz   +11 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Translational and rotational motions of albumin sensed by a non-covalent associated porphyrin under physiological and acidic conditions: a fluorescence correlation spectroscopy and time resolved anisotropy study.

, 2008
The interaction between a free-base, anionic water-soluble porphyrin, TSPP, and the drug carrier protein, bovine serum albumin (BSA) has been studied by time-resolved fluorescence anisotropy (TRFA) and fluorescence correlation spectroscopy (FCS) at two ...
Costa, S.M., Hoek, A., van, Borst, J.W., Visser, A.J.W.G., Andrade, S.M.   +4 more
core   +1 more source

Interferometric fluorescence cross correlation spectroscopy.

PLoS ONE, 2019
Measuring transport properties like diffusion and directional flow is essential for understanding dynamics within heterogeneous systems including living cells and novel materials.
Ipsita Saha, Saveez Saffarian
doaj   +1 more source

A Decoy Peptide that Disrupts TIRAP Recruitment to TLRs Is Protective in a Murine Model of Influenza

Cell Reports, 2015
Toll-like receptors (TLRs) activate distinct, yet overlapping sets of signaling molecules, leading to inflammatory responses to pathogens. Toll/interleukin-1 receptor (TIR) domains, present in all TLRs and TLR adapters, mediate protein interactions ...
Wenji Piao, Kari Ann Shirey, Lisa W. Ru, Wendy Lai, Henryk Szmacinski, Greg A. Snyder, Eric J. Sundberg, Joseph R. Lakowicz, Stefanie N. Vogel, Vladimir Y. Toshchakov   +9 more
doaj   +1 more source

Supramolecular association studied by Fluorescence correlation spectroscopy

Frontiers in Chemistry, 2022
A comprehensive description of a supramolecular system involves a full understanding of its thermodynamic and dynamic properties, as well as detailed knowledge of its structure. Fluorescence Correlation Spectroscopy (FCS) constitutes a powerful technique
Mercedes Novo, Wajih Al-Soufi
doaj   +1 more source