Results 51 to 60 of about 513,540 (340)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

First Design of a Contact Lens for Diagnosis of Dehydration

Biosensors
Dehydration is a serious medical problem for elderly patients and young children. The most widely used diagnostics are measurements of sodium ion (Na+) and potassium ion (K+) in blood serum.
Kundan Sivashanmugan, Reece E. Albert, Joseph R. Lakowicz   +2 more
doaj   +1 more source

Application of Curve Fitting and Radial Basis Function in the Quantitative Analysis of Molecular Fluorescence Spectroscopy

Chemical Engineering Transactions, 2018
The fluorescence of Lactobacillus plantarum solution was characterized by two-dimensional fluorescence spectroscopy and three-dimensional fluorescence spectroscopy and the quantitative detection of the fluorescence peak intensity of Lactobacillus ...
Huan Guo
doaj   +1 more source

A Comprehensive Review of Fluorescence Correlation Spectroscopy

Frontiers in Physics, 2021
Fluorescence correlation spectroscopy (FCS) is a powerful technique for quantification of molecular dynamics, and it has been widely applied in diverse fields, e.g., biomedicine, biophysics, and chemistry.
Lan Yu, Yunze Lei, Ying Ma, Min Liu, Juanjuan Zheng, Dan Dan, Peng Gao   +6 more
doaj   +1 more source

Chloroplast and Cell Imaging at Submicron Resolution by Two-Photon Excitation [PDF]

, 2012
Novel, two-photon NIR excitation fluorescence correlation microspectroscopy tests and preliminary results were presented in this article with submicron resolution for concentrated suspensions of functional cells and chloroplast membranes.
I C. Baianu
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Xanthines Studied via Femtosecond Fluorescence Spectroscopy

Molecules, 2016
Xanthines represent a wide class of compounds closely related to the DNA bases adenine and guanine. Ubiquitous in the human body, they are capable of replacing natural bases in double helices and give rise to four-stranded structures. Although the use of
Pascale Changenet-Barret, Lajos Kovács, Dimitra Markovitsi, Thomas Gustavsson   +3 more
doaj   +1 more source

Supramolecular association studied by Fluorescence correlation spectroscopy

Frontiers in Chemistry, 2022
A comprehensive description of a supramolecular system involves a full understanding of its thermodynamic and dynamic properties, as well as detailed knowledge of its structure. Fluorescence Correlation Spectroscopy (FCS) constitutes a powerful technique
Mercedes Novo, Wajih Al-Soufi
doaj   +1 more source

Polymer dynamics, fluorescence correlation spectroscopy, and the limits of optical resolution

, 2012
In recent years, fluorescence correlation spectroscopy has been increasingly applied for the study of polymer dynamics on the nanometer scale. The core idea is to extract, from a measured autocorrelation curve, an effective mean-square displacement ...
Jörg Enderlein, V. Lisy
core   +1 more source