Results 61 to 70 of about 513,540 (340)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Fluorescence spectroscopy applied in lubricant oils

open access: yesOrbital: The Electronic Journal of Chemistry, 2018
In this work, we report the use of the fluorescence spectroscopy to identify lubricant oils. Optical characterization was performed in four commercial lubricant oils that are used in the reciprocating compressors.
Claudio Yamamoto Morassuti   +3 more
doaj   +1 more source

Detection strategies for bioassays based on liquid chromatography, fluorescence spectroscopy and mass spectrometry [PDF]

open access: yes, 2005
New detection strategies for bioassays based on liquid chromatography,\ud fluorescence spectroscopy and mass spectrometry were developed and are\ud presented within this ...
Hempen, Christel Maria
core   +1 more source

A model for predicting dissolved organic carbon distribution in a reservoir water using fluorescence spectroscopy [PDF]

open access: yes, 2004
A number of water treatment works (WTW) in the north of England (UK) have experienced problems in reducing the dissolved organic carbon (DOC) present in the water to a sufficiently low level.
Banks, Jenny   +6 more
core   +3 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Graphene oxide: Synthesis and laser spectroscopy approach

open access: yesOptical Materials: X
Nanotechnology research offers advancements in materials and industrial uses such as nano-electronics, medical sciences, fuel, biology, and technological innovation.
Diaa Atta   +3 more
doaj   +1 more source

Measurement and simulation of laser-induced fluorescence from non-equilibrium ultracold neutral plasmas

open access: yes, 2009
We report new measurements and simulations of laser-induced fluorescence in ultracold neutral plasmas. We focus on the earliest times, when the plasma equilibrium is evolving and before the plasma expands.
Bergeson, S. D.   +2 more
core   +1 more source

Time-resolved Raman spectroscopy for in situ planetary mineralogy [PDF]

open access: yes, 2010
Planetary mineralogy can be revealed through a variety of remote sensing and in situ investigations that precede any plans for eventual sample return. We briefly review those techniques and focus on the capabilities for on-surface in situ examination of ...
Blacksberg, Jordana   +2 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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