Results 71 to 80 of about 262,308 (303)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Feedback Tracking and Correlation Spectroscopy of Fluorescent Nanoparticles and Biomolecules [PDF]

, 2008
The best way to study dynamic fluctuations in single molecules or nanoparticles is to look at only one particle at a time, and to look for as long as possible.
McHale, Kevin L.
core   +1 more source

Case study of fluorite mineralization using traditional and laser spectroscopic techniques, homret akarem area south eastern desert, Egypt

Optical Materials: X
Green fluorite samples from Homret Akarem, eastern desert Egypt, were investigated by laser-based Raman spectroscopy to study the effect of rare earth elements (REEs) and natural radiation from the surrounding environment on their physico-chemical ...
Diaa Atta, Tarek A. Abdel-Halim, Doaa A. Mostafa, Fatma M. Zaher   +3 more
doaj   +1 more source

Structural Analysis of Humic Acid in Soil at Different Corn Straw Returning Modes through Fluorescence Spectroscopy and Infrared Spectroscopy

International Journal of Analytical Chemistry, 2019
The purpose of this study is to analyze the effects of different straw returning modes on the structure of humic acid (HA) in soil by fluorescence spectroscopy and infrared (IR) spectroscopy.
JinFeng Gao, Sen Dou, ZhiGuo Wang
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Combined information from Raman spectroscopy and optical coherence tomography for enhanced diagnostic accuracy in tissue discrimination

, 2014
We thank the UK EPSRC for funding, the CR-UK/EPSRC/MRC/DoH (England) imaging programme, the European Union project FAMOS (FP7 ICT, contract no. 317744) and the European Union project IIIOS (FP7/2007-2013, contract no. 238802).
C. Simon Herrington, Bavishna B. Praveen, Herrington, C.S., Andrew Riches, Bellini, N., Ashok, P.C., Praveen, B.B., Nicola Bellini, Riches, A., Dholakia, K., Praveen C. Ashok, Kishan Dholakia   +11 more
core   +1 more source

Photophysics of phycoerythrocyanins from the cyanobacterium Westiellopsis prolifica studied by time-resolved fluorescence and coherent anti-Stokes Raman scattering spectroscopy [PDF]

, 1994
Three building blocks of the antenna complexes of the cyanobacterium Westiellopsis prolifica were studied: PEC(X), which is similar to the α-subunit of phycoerythrocyanin (PEC), trimers of PEC and monomers derived from these by deaggregation with KSCN ...
F. Lottspeich, G. Brehm, C.-J. Prenzel, W. Jäger, Jäger, W., S. Schneider, Lottspeich, Fritz, Scheer, Hugo, Schneider, Siegfried, P.S.Maruthi Sai, H. Scheer, Brehm, G., Maruthi Sai, P. S., Prenzel, C. J.   +13 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

In-vivo optical detection of cancer using chlorin e6 – polyvinylpyrrolidone induced fluorescence imaging and spectroscopy

BMC Medical Imaging, 2009
Background Photosensitizer based fluorescence imaging and spectroscopy is fast becoming a promising approach for cancer detection. The purpose of this study was to examine the use of the photosensitizer chlorin e6 (Ce6) formulated in polyvinylpyrrolidone
Soo Khee, Bhuvaneswari Ramaswamy, Thong Patricia SP, Chin William WL, Heng Paul WS, Olivo Malini   +5 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source