Results 201 to 210 of about 35,262 (243)

Concomitant immunity against superimposed homologous Echinostoma caproni infections in mice is mediated by interleuquin-25. [PDF]

Mem Inst Oswaldo Cruz
Cociancic P, Fiallos E, Esteban JG, Muñoz-Antoli C, Toledo R.   +4 more
europepmc   +1 more source

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

Advanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li, Chang Liu, Zhaoxue Ma, Dongyou Zheng, Renkai Wang, Yongjing Yu, Guangmin Chen, Chenglong Li, Yue Bu, Hang Cao, Bing Zhang   +10 more
wiley   +1 more source

Preparation of Testicular Cells for Immunofluorescence Analysis of Manchette in Elongating Spermatids. [PDF]

Bio Protoc
Niu C, Dhikhirullahi O, Zhang Z.
europepmc   +1 more source

GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer

Advanced Science, EarlyView.
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello, Sandra Hauser, Michael Seifert, Christopher K. Barlow, Joel R. Steele, Emma Salisbury, Daniel Croagh, Kathryn S. Stok, Anna V. Taubenberger, Ralf B. Schittenhelm, Daniela Loessner   +10 more
wiley   +1 more source

Assessing Commercial Tissue-Based Assays for Autoimmune Neurologic Disorders (II): Antibodies to Surface Antigens. [PDF]

Neurol Neuroimmunol Neuroinflamm
Papi C, Milano C, Arlettaz L, Businaro P, Marmolejo L, Naranjo L, Planagumà J, Martinez-Hernandez E, Armangué T, Guasp M, Ruiz-García R, Aguilar E, Gastaldi M, Iorio R, Gaig C, Saiz A, Sabater L, Graus F, Dalmau JO, Spatola M.   +19 more
europepmc   +1 more source

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

Advanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen, Ling Wang, Hongmei Fan, Lisheng Li, Lingyu Zhang, Ruoxin Li, Fang Liu, Fuli Wen, Yunbin Ye, Chuanzhong Huang   +9 more
wiley   +1 more source

Bioorthogonal Chemistry in Biomolecule Quantification: A Review of Reactions and Strategies. [PDF]

Chemistry
Yang M, Wang S.
europepmc   +1 more source

Advances in pathogen detection of <i>Pneumocystis jirovecii</i> pneumonia. [PDF]

Infect Med (Beijing)
Bai L, Li Y, Li Y, Hu C, Zhao B.
europepmc   +1 more source

A novel single-vector featuring bidirectional promoters for production of bispecific antibody against rabies virus. [PDF]

BMC Biotechnol
Zhang Z, Li J, Lin G, Cao S, Wu Y.
europepmc   +1 more source

Serum Onconeural Antibodies in Dogs and Cats for Early Diagnosis of Cancer. [PDF]

Vet Med (Auckl)
Agassandian M, Agassandian K.
europepmc   +1 more source