The Response of Cerebral Cortex to Haemorrhagic Damage: Experimental Evidence from a Penetrating Injury Model [PDF]
Understanding the response of the brain to haemorrhagic damage is important in haemorrhagic stroke and increasingly in the understanding the cerebral degeneration and dementia that follow head trauma and head-impact sports.
Johnstone, Daniel M.+4 more
core +1 more source
Adult human case of toxocariasis with pulmonary migratory infiltrate and eosinophilia [PDF]
Introduction. Toxocariasis is a zoonosis which is in Serbia characterized with a very high infection rate of dogs and excessive contamination of the soil with the eggs of Toxocara canis, the agent of the disease.
Považan Đorđe+6 more
doaj +1 more source
CERTAIN TECHNICAL ASPECTS OF FLUORESCENCE MICROSCOPY AND THE COONS FLUORESCENT ANTIBODY TECHNIQUE [PDF]
A fluorescence microscope possessing an efficient ultraviolet light source, the 1000 watt A-H6, is described with special reference to its application in studies concerned with the fluorescent antibody technique and the tissue localization of the tetracyclines. The spectral characteristics of the light source are discussed and methods outlined whereby
openaire +3 more sources
Development and optimization of a miniaturized western blot-based screening platform to identify regulators of post-translational modifications [PDF]
Post-translational modifications (PTMs) are fundamental traits of protein functionality and their study has been addressed using several approaches over the past years.
Gottifredi, Vanesa+2 more
core +1 more source
Effect of the Protein Corona Formation on Antibody Functionalized Liquid Lipid Nanocarriers [PDF]
The main aim of this study is to report basic knowledge on how a protein corona (PC) could affect or modify the way in which multifunctionalized nanoparticles interact with cells. With this purpose, we have firstly optimized the development of a target-specific nanocarrier by coupling a specific fluorescent antibody on the surface of functionalized ...
arxiv +1 more source
ABCC6 is a basolateral plasma membrane protein [PDF]
RATIONALE:: ABCC6 plays a crucial role in ectopic calcification; mutations of the gene cause pseudoxanthoma elasticum and general arterial calcification of infancy.
Apana, A.+11 more
core +3 more sources
Intracellular staining is a widely used flow cytometry (FCM)-based technique to detect the expression of cytoslio nucleic antigens. However, intracellular staining of cells expressing cytosolic fluorescent protein (FP) markers was proven to be ...
Maria Grupillo+6 more
doaj +1 more source
Cross-Gate MLP with Protein Complex Invariant Embedding is A One-Shot Antibody Designer [PDF]
Antibodies are crucial proteins produced by the immune system in response to foreign substances or antigens. The specificity of an antibody is determined by its complementarity-determining regions (CDRs), which are located in the variable domains of the antibody chains and form the antigen-binding site. Previous studies have utilized complex techniques
arxiv
Role of the CXCR4/ALK5/Smad3 Signaling Pathway in Cancer-Induced Bone Pain
Chong Peng,1,* Xue-Tai Chen,1,* Heng Xu,2 Li-Ping Chen,2 Wen Shen1,2 1Jiangsu Province Key Laboratory of Anesthesiology and Jiangsu Province Key Laboratory of Anesthesia and Analgesia Application Technology, Xuzhou Medical University, Xuzhou, Jiangsu ...
Peng C, Chen XT, Xu H, Chen LP, Shen W
doaj
The spatiotemporal localization of different intracellular factors in real-time and their detection in live cells are important parameters to understand dynamic protein-based processes.
Sascha Conic+3 more
doaj +1 more source