Results 71 to 80 of about 427,237 (379)

Adult human case of toxocariasis with pulmonary migratory infiltrate and eosinophilia [PDF]

Vojnosanitetski Pregled, 2011
Introduction. Toxocariasis is a zoonosis which is in Serbia characterized with a very high infection rate of dogs and excessive contamination of the soil with the eggs of Toxocara canis, the agent of the disease.
Považan Đorđe, Đurić Mirna, Uzurov-Dinić Vera, Lalošević Dušan, Lalošević Vesna, Sečen Svetozar, Považan Anika   +6 more
doaj   +1 more source

A surgical model of short bowel syndrome induces a long-lasting increase in pancreatic beta-cell mass [PDF]

, 2015
Several surgical techniques are used nowadays as a severe treatment for obesity and diabetes mellitus type 2. These techniques are aggressive due to drastic changes in the nutrient flow and non-reversible modifications on the digestive tube.
Aguilar Diosdado, Manuel, Camacho Ramírez, Alonso, Lechuga Sancho, Alfonso María, Prada Oliveira, José Arturo, Pérez Arana, Gonzalo Martín, Sancho Maraver, Eva, Segundo Iglesias, María del Carmen   +6 more
core   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Impact of Concordance Between Antinuclear Antibody Indirect Immunofluorescence Patterns and Myositis Antibodies in Idiopathic Inflammatory Myopathies: Study Protocol

Acta Médica Portuguesa
Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of systemic autoimmune rheumatic disorders in which chronic inflammation of skeletal muscle leads to muscle weakness. Many other organs, including the skin, heart, lungs, and joints, may
Cláudia Pinto Oliveira, Mariana Pereira Silva, Carolina Vilafanha, Graça Costa, Mariana Emília Santos, Maria João Gonçalves, Priscila Silva, Vânia Fernandes, Tiago Meirinhos, Catarina Almeida, Ana Rita Prata, Anabela Barcelos, Raquel Campanilho-Marques, Eduardo Dourado   +13 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Patterns of gene expression in schistosomes: localization by whole mount in situ hybridization [PDF]

, 2007
rom the identification of genes to the characterization of their functions and interactions. Developmental biologists have long used whole mount in situ hybridization (WISH) to determine gene expression patterns, as a vital tool for formulating and ...
Davis, G. P. DILLON, H. V. ISAACS, J. C. ILLES, Pownall, R. A. WILSON, Skelly, Wilson   +7 more
core   +1 more source

An improved intracellular staining protocol for efficient detection of nuclear proteins in YFP-expressing cells

BioTechniques, 2011
Intracellular staining is a widely used flow cytometry (FCM)-based technique to detect the expression of cytoslio nucleic antigens. However, intracellular staining of cells expressing cytosolic fluorescent protein (FP) markers was proven to be ...
Maria Grupillo, Robert Lakomy, Xuehui Geng, Alexis Styche, William A Rudert, Massimo Trucco, Yong Fan   +6 more
doaj   +1 more source

Prevalence of Enteropathogens in Dogs Attending 3 Regional Dog Parks in Northern California. [PDF]

, 2016
BackgroundThe prevalence and risk factors for infection with enteropathogens in dogs frequenting dog parks have been poorly documented, and infected dogs can pose a potential zoonotic risk for owners.Hypothesis/objectivesTo determine the prevalence and ...
Ahlmann, A, Hascall, KL, Kass, PH, Lappin, MR, Marks, SL, Saksen, J, Scorza, AV   +6 more
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Role of the CXCR4/ALK5/Smad3 Signaling Pathway in Cancer-Induced Bone Pain

Journal of Pain Research, 2020
Chong Peng,1,* Xue-Tai Chen,1,* Heng Xu,2 Li-Ping Chen,2 Wen Shen1,2 1Jiangsu Province Key Laboratory of Anesthesiology and Jiangsu Province Key Laboratory of Anesthesia and Analgesia Application Technology, Xuzhou Medical University, Xuzhou, Jiangsu ...
Peng C, Chen XT, Xu H, Chen LP, Shen W
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