Results 111 to 120 of about 516,362 (300)

Bright fluorescent silica-nanoparticle probes for high-resolution STED and confocal microscopy

open access: yesBeilstein Journal of Nanotechnology, 2017
In recent years, fluorescent nanomaterials have gained high relevance in biological applications as probes for various fluorescence-based spectroscopy and imaging techniques.
Isabella Tavernaro   +3 more
doaj   +1 more source

Development of a Novel Q-body Using an In Vivo Site-Specific Unnatural Amino Acid Incorporation System

open access: yesSensors, 2018
A Q-body capable of detecting target molecules in solutions could serve as a simple molecular detection tool. The position of the fluorescent dye in a Q-body affects sensitivity and therefore must be optimized.
Yoichi Kurumida, Nobuhiro Hayashi
doaj   +1 more source

The oral-aboral axis of a sea urchin embryo is specified by first cleavage [PDF]

open access: yes, 1989
Several lines of evidence suggest that the oral-aboral axis in Strongylocentrotus purpuratus embryos is specified at or before the 8-cell stage. Were the oral-aboral axis specified independently of the first cleavage plane, then a random association of ...
Britten, Roy J.   +3 more
core  

Visualizing mitochondrial FoF1-ATP synthase as the target of the immunomodulatory drug Bz-423

open access: yes, 2018
Targeting the mitochondrial enzyme FoF1-ATP synthase and modulating its catalytic activities with small molecules is a promising new approach for treatment of autoimmune diseases. The immuno-modulatory compound Bz-423 is such a drug that binds to subunit
Börsch, Michael   +2 more
core   +1 more source

Marking microelectrode penetrations with fluorescent dyes

open access: yesJournal of Neuroscience Methods, 1996
Fluorescent dyes were used to mark and identify the tracks left by extracellular microelectrodes in neurophysiological experiments. Forty-two penetrations were made into the postcentral gyrus of 3 Macaque monkeys with electrodes coated with 1 of 5 fluorescent dyes (DiI, DiO, DiI-C5, PyPO, and Fast Blue). The electrodes were driven at rates ranging from
J J, DiCarlo   +3 more
openaire   +2 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Improved direct-count method by fluorescence microscope for low-biomass ice core

open access: yesAntarctic Record, 2012
Ice cores recovered from ice sheets contain microorganisms that were transported to the surface of the ice sheet along with airborne dust. The abundance of microorganisms in ice cores, as measured by direct cell count under a fluorescence microscope, is ...
Jun Uetake   +2 more
doaj   +1 more source

Microfluidic droplet control by photothermal interfacial flow [PDF]

open access: yes, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014)   +2 more
core  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Efficient Mixing at low Reynolds numbers using polymer additives

open access: yes, 2001
Mixing in fluids is a rapidly developing field of fluid mechanics \cite{Sreen,Shr,War}, being an important industrial and environmental problem. The mixing of liquids at low Reynolds numbers is usually quite weak in simple flows, and it requires special ...
A Groisman   +16 more
core   +1 more source

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