Results 91 to 100 of about 340,246 (317)

Deep Learning-Driven Intelligent Fluorescent Probes: Advancements in Molecular Design for Accurate Food Safety Detection

Foods
The complexity of global food supply chains challenges public health, requiring advanced detection technologies beyond traditional lab methods. Fluorescent sensing, known for its sensitivity and quick response, is promising for food safety but hindered ...
Yongqiang Shi, Sisi Yang, Wenting Li, Yuqing Wu, Weiran Luo   +4 more
doaj   +1 more source

A Fluorescent Coumarin-Based Probe for the Fast Detection of Cysteine with Live Cell Application

Molecules, 2017
A new coumarin-based fluorescent probe, containing an allylic esters group, has been designed and synthesized for sensing cysteine in physiological pH. In this fluorescent probe, the coumarin was applied as the fluorophore and an allylic esters group was
Rui-Feng Zeng, Jin-Shuai Lan, Xiao-Die Li, Hui-Fen Liang, Yan Liao, Ying-Jie Lu, Tong Zhang, Yue Ding   +7 more
doaj   +1 more source

Silver(I) ion detection in aqueous media based on "off-on" fluorescent probe

, 2012
A novel and easily available fluorescent probe bearing naphthalimide and thiosemicarbazide groups has been designed. The probe H1 displays high selectivity and sensitivity to Ag+ over other metal ions in aqueous media.A novel and easily available ...
Yu, Chunwei, Chen, Lingxin, Ding, Mingyu, Zhang, Jun   +3 more
core  

Combination of small molecule microarray and confocal microscopy techniques for live cell staining fluorescent dye discovery

, 2013
Discovering new fluorochromes is significantly advanced by high-throughput screening (HTS) methods. In the present study a combination of small molecule microarray (SMM) prescreening and confocal laser scanning microscopy (CLSM) was developed in order to
Bhavyashree Suresh, Ferhan Ayaydin, Bokros, Attila, Eszter Molnár, Peksel, Begüm, Ágnes Medgyesi, Liliána Fehér, Pradeep Kumar Reddy Cingaram, Puskás, László G., Soujanya Kuntam, Attila Bokros, Begüm Peksel, Gabriella Fábián, Molnár, Eszter, László G. Puskás, Kuntam, Soujanya, Liliána Z. Fehér, Fábián, Gabriella, László Puskás, Cingaram, Pradeep Kumar Reddy, Pradeep Cingaram   +20 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A simple coumarin-based system for the effective detection of superoxide in bacteria

Results in Chemistry
Superoxide anion is a highly reactive ROS however the sensing of this species is relatively unexplored. The current methods to sense superoxide requires the construction of complex probes which are often hard to synthesize. With this research we report a
Kai-Cheng Yan, Qiao Cao, Naing Thet, Adam C. Sedgwick, Tony D. James, A. Toby A. Jenkins   +5 more
doaj   +1 more source

Morphological detection of X- and Y-chromosomes in smears and paraffin-embedded tissues using a non-isotopic in situ hybridization technique (NISH) [PDF]

, 1994
Pharyngeal smears and paraffin-embedded tissue specimens (skeletal muscle, kidney) obtained from 10 male and 10 female individuals were evaluated using non-isotopic in situ hybridization (NISH) with commercial X- and Y-specific biotinylated probes which ...
Eisenmenger, Wolfgang, Nerlich, A., Tübel, J., Betz, P., Baretton, G.   +4 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

A Near-IR Reversible Fluorescent Probe Modulated by Selenium for Monitoring Peroxynitrite and Imaging in Living Cells

, 2011
A Near-IR Reversible Fluorescent Probe Modulated by Selenium for Monitoring Peroxynitrite and Imaging in Living CellsWe have developed a near-IR reversible fluorescent probe containing an organoselenium functional group that can be used for the highly ...
Zhao, Guangjiu, Yu, Fabiao, 韩克利, Li, Guangyue, Chu, Tianshu, Li, Peng, Han, Keli   +6 more
core   +1 more source