Results 11 to 20 of about 558,671 (204)

3D spatially-resolved optical energy density enhanced by wavefront shaping [PDF]

, 2017
We study the three-dimensional (3D) spatially-resolved distribution of the energy density of light in a 3D scattering medium upon the excitation of open transmission channels.
Hong, Peilong, Lagendijk, Ad, Mosk, Allard P., Ojambati, Oluwafemi S., Vos, Willem L.   +4 more
core   +25 more sources

Fluorescence-based proteasome activity profiling [PDF]

, 2012
With the proteasome emerging as a therapeutic target for cancer treatment, accurate tools for monitoring proteasome (inhibitor) activity are in demand.
Berkers, C.R., Jong, A., Ovaa, H., Rodenko, B., Schuurman, K.G.   +4 more
core   +1 more source

Noninvasive depth estimation using tissue optical properties and a dual-wavelength fluorescent molecular probe in vivo [PDF]

, 2017
Translation of fluorescence imaging using molecularly targeted imaging agents for real-time assessment of surgical margins in the operating room requires a fast and reliable method to predict tumor depth from planar optical imaging.
Achilefu, Samuel, Lam, Jesse, Maji, Dolonchampa, Miller, Jessica P, Tromberg, Bruce J   +4 more
core   +2 more sources

Ubiquitin-based probes prepared by total synthesis to profile the activity of deubiquitinating enzymes [PDF]

, 2012
Epitope-tagged active-site-directed probes are widely used to visualize the activity of deubiquitinases (DUBs) in cell extracts, to investigate the specificity and potency of small-molecule DUB inhibitors, and to isolate and identify DUBs by mass ...
Berlin, I., de Jong, A., El Atmioui, D., Merkx, R., Neefjes, J.J., Ovaa, H., Robson, C.N., Rodenko, B., Wijdeven, R.H.M., Yalçin, Z.   +9 more
core   +1 more source

The Application of Nucleic Acid Probe–Based Fluorescent Sensing and Imaging in Cancer Diagnosis and Therapy

Frontiers in Chemistry, 2021
It is well known that cancer incidence and death rates have been growing, but the development of cancer theranostics and therapeutics has been a challenging work. Recently, nucleic acid probe–based fluorescent sensing and imaging have achieved remarkable
Ge Huang, Ge Huang, Chen Su, Lijuan Wang, Lijuan Wang, Yanxia Fei, Jinfeng Yang   +6 more
doaj   +1 more source

Dual-modal SERS/fluorescence AuNP probe for mitochondrial imaging [PDF]

, 2017
A novel SERS/fluorescent multimodal imaging probe for mitochondria has been synthesised using 12 nm diameter gold nanoparticles (AuNP) surface functionalised with a rhodamine thiol derivative ligand.
Beija, Best, Brindle, Chen, Doubrovin, Duchen, Enüstün, Frens, Ghosh, Gonçalves, Hockings, Huang, Jaworska, Jennings, Kimling, Lavis, Lee, Lee, Lefevre, Lin, Longmire, Mayer, Pan, Rivas, Rivas, Saha, Scaduto, Stasiuk, Stasiuk, Stuchinskaya, Suksai, Sun, Sung, Wang, You, Yuan, Zhou   +36 more
core   +1 more source

Color-Switchable Nanosilicon Fluorescent Probes

ACS Nano, 2022
Fluorescent probes are vital to cell imaging by allowing specific parts of cells to be visualized and quantified. Color-switchable probes (CSPs), with tunable emission wavelength upon contact with specific targets, are particularly powerful because they not only eliminate the need to wash away all unbound probe but also allow for internal controls of ...
Huai Chen, Jiang Xu, Yaping Wang, Da Wang, Raquel Ferrer-Espada, Yutong Wang, Jingjian Zhou, Adrián Pedrazo-Tardajos, Mei Yang, Jia-Heng Tan, Xiaoyu Yang, Lei Zhang, Ilya Sychugov, Shoudeng Chen, Sara Bals, Johan Paulsson, Zhenyu Yang   +16 more
openaire   +3 more sources

Comparison of two fluorescent probes in preclinical non-invasive imaging and image-guided debridement surgery of Staphylococcal biofilm implant infections

Scientific Reports, 2021
Implant-associated infections are challenging to diagnose and treat. Fluorescent probes have been heralded as a technologic advancement that can improve our ability to non-invasively identify infecting organisms, as well as guide the inexact procedure of
Howard Y. Park, Stephen D. Zoller, Vishal Hegde, William Sheppard, Zachary Burke, Gideon Blumstein, Christopher Hamad, Marina Sprague, John Hoang, Ryan Smith, Francisco Romero Pastrana, Julie Czupryna, Lloyd S. Miller, Marina López-Álvarez, Mafalda Bispo, Marleen van Oosten, Jan Maarten van Dijl, Kevin P. Francis, Nicholas M. Bernthal   +18 more
doaj   +1 more source

Novel Fluorescent Probe Based on Anthryl Dendron Having Oligo(ethyleneoxide) Groups at the Terminals [PDF]

, 2008
Amphiphilic anthryl dendrons 5 and 6, which have carboxylate groups or oligo(ethyleneoxide) groups at the terminals, show solvatochromic properties. Reaction efficiency of photodimerization and dynamic light scattering (DLS) experiment of 5 and 6 reveal ...
Takaguchi, Yutaka, Yanagimoto, Yasushi
core   +1 more source

Theoretical Insights into a Near-Infrared Fluorescent Probe NI-VIS Based on the Organic Molecule for Monitoring Intracellular Viscosity

Molecules, 2023
So many biological functional disorders and diseases, such as atherosclerosis, hypertension, diabetes, Alzheimer’s disease, as well as cell malignancy are closely related with the intracellular viscosity.
Yongjin Peng, He Huang, Yuling Liu, Xiaoyan Zhao   +3 more
doaj   +1 more source