Results 41 to 50 of about 340,246 (317)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Modulating absorption and emission of smart fluorescent organic probes through tailored physicochemical properties

Scientific Reports
The newly fabricated fluorescent organic nanoparticles (FONs) with size 80.94 nm as renowned contender has facile synthesis, robust tunable fluorescence, unique optical properties and great potential in sensing at trace level.
Muhammad Atif, Zaman Ashraf, Farhat Yasmeen, Muhammad Iqbal, Moeen Anjum   +4 more
doaj   +1 more source

New Fluorescence Probes for Biomolecules [PDF]

Molecules, 2015
Steady state fluorescence measurements have been used for the investigation of interaction between the bovine serum albumin (BSA) and fluorescence probes: 3-hydroxy-2,4- bis[(3-methyl-1,3-benzoxazol-2(3H)-ylidene)methyl]cyclobut-2-en-1-one (SQ6), 3-hydroxy- 2,4-bis[(3-methyl-1,3-benzothiazol-2(3H)-ylidene)methyl]cyclobut-2-en-1-one (SQ7) and 3-hydroxy ...
Katarzyna Jurek, Janina Kabatc, Katarzyna Kostrzewska, Marlena Grabowska   +3 more
openaire   +3 more sources

A two-photon fluorescent probe for imaging hydrogen sulfide in living cells

, 2013
Fluorescent probes for hydrogen sulfide have received considerable attention because of the biological significance of H2S recognized recently. Two-photo microscopy offers advantages of increased penetration depth, localized excitation, and prolonged ...
Zou, Chunyan, Zhang, Xinfu, Qiao, Qinglong, Xu, Zhaochao, Jingnan Cui, Liu, Tianyu, Cui, Jingnan, Feng, Lei, 徐兆超   +8 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Development of TaqMan probe-based insulated isothermal PCR (iiPCR) for sensitive and specific on-site pathogen detection. [PDF]

PLoS ONE, 2012
Insulated isothermal PCR (iiPCR), established on the basis of Ralyeigh-Bénard convection, is a rapid and low-cost platform for nucleic acid amplification.
Yun-Long Tsai, Hwa-Tang Thomas Wang, Hsiao-Fen Grace Chang, Chuan-Fu Tsai, Ching-Ko Lin, Ping-Hua Teng, Chen Su, Chien-Chung Jeng, Pei-Yu Lee   +8 more
doaj   +1 more source

A DIE responsive NIR-fluorescent cell membrane probe

, 2018
It is challenging to achieve selective off to on modulation of the emissive state of a fluorophore within a complex and heterogeneous cellular environment.
Cheung, Shane, Durán Sampedro, Gonzalo, Chen, Zhi-Long, O'Shea, Donal, Cahill, Ronan, Wu, Dan   +5 more
core   +1 more source

A photoacoustic-fluorescent imaging probe for proteolytic gingipains expressed by Porphyromonas gingivalis

, 2022
Porphyromonas gingivalis is a keystone pathogen in periodontal disease. We herein report a dual-modal fluorescent and photoacoustic imaging probe for the detection of gingipain proteases secreted by P. gingivalis.
Natalia, Tjokro, Kai Chiao, Chang, Jesse, Jokerst, Brendan, Zhang, Mohammed, Hayati, Casey, Chen, Colman, Moore, Yong, Cheng   +7 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Synthesis and Fluorescent Properties of Aminopyridines and the Application in “Click and Probing”

Molecules, 2022
Unsubstituted pyridin-2-amine has a high quantum yield and is a potential scaffold for a fluorescent probe. However, the facile access to conjugated highly substituted aminopyridines and the study of their fluorescent properties is scarce. In this paper,
Zongyang Li, Yaxuan Li, Wenxu Chang, Sen Pang, Xuefeng Li, Liusheng Duan, Zhenhua Zhang   +6 more
doaj   +1 more source