Results 61 to 70 of about 340,246 (317)

Fluorescent Probes of Biological Membranes [PDF]

Proceedings of the National Academy of Sciences, 1970
Fluorescent and phosphorescent probes that have readily interpretable emission properties can be specifically inserted into biological macromolecules to reveal facets of their structure and dynamics: (1) Proximity . Singlet-singlet and triplet-singlet energy transfer can serve as spectroscopic rulers in the 10-65 Å ...
A S, Waggoner, L, Stryer
openaire   +2 more sources

A Colorimetric Fluorescent Probe for SO2 Derivatives-Bisulfite and Sulfite at Nanomolar Level

, 2017
A colorimetric fluorescent probe with fluorescence emission feature sensitive to SO2 derivatives, i.e. bisulfite (HSO3 (-)) and sulfite (SO3 (2-)), was developed based on the HSO3 (-)/SO3 (2-)-mediated nucleophilic addition reaction of the probe that ...
Zhang, Yuanlin, Lv, Yanlin, Zhang, Jian, Zhang, Guangjin, Wang, Xuefei, Peng, Aidong, Tian, Zhiyuan   +6 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A Near-Infrared Ratiometric Fluorescent Probe for Detecting Endogenous Cu2+ in the Brain

, 2023
Copper participates in a range of critical functions in the nervous system in the human brain. Disturbances in brain copper content is strongly associated with neurological disease.
Tom, Hawtrey, Jourdin R. C. , Rouaen, Orazio , Vittorio, Carolyn, Ohno, Marcus E. , Graziotto, Kay L. , Double, Elizabeth J. , New, Veronica , Cottam, Marcus , Heisler, Jianping, Zhu   +9 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

A novel cassette method for probe evaluation in the designed biochips [PDF]

, 2013
A critical step in biochip design is the selection of probes with identical hybridisation characteristics. In this article we describe a novel method for evaluating DNA hybridisation probes, allowing the fine-tuning of biochips, that uses cassettes with ...
Julian Mitchell (572357), Irina Bogdarina, Abdulmohsen A. Al-Humam (572361), Nelly Sapojnikova (572356), Bogdarina, Irina, Vitaly Zinkevich, Sapojnikova, Nelly, Mitchell, Julian, Julian Mitchell, Al-humam, Abdulmohsen A., Nino Asatiani (572359), Zinkevich, Vitaly, Samia Alkhalil (572360), Abdulmohsen A Al-Humam, Nelly Sapojnikova, Irina Bogdarina (367051), Tamar Kartvelishvili, Vitaly Zinkevich (572355), Samia Alkhalil, Kartvelishvili, Tamar, Abdulmohsen A. Al-humam, Nino Asatiani, Alkhalil, Samia, Tamar Kartvelishvili (572358), Asatiani, Nino   +24 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

The Detection of Lymph Node Metastasis Metastases Using a Near-Infrared Fluorescent Probe Based on Tumor-Targeted Monoclonal Antibody Antibodies Specific: A Prospective Study in a Nude Mouse Model

Clinical and Experimental Obstetrics & Gynecology
Background: To identify the metastatic lymph nodes and remove them accurately, the fluorescent surgical navigation ability of the ovarian cancer-specific fluorescent probe COC183B2-800 was assessed to verify the metastatic lymph nodes ...
Huarui Yang, Yijun Zhang, Chongyuan Zhu, Yi Zhu, Xuelian Song, Xiaohong Chang, Yi Li   +6 more
doaj   +1 more source

A Fluorescent Probe for Diacetyl Detection [PDF]

Journal of Fluorescence, 2008
A water-soluble fluorescent probe, rhodamine B hydrazide (RBH), was prepared and its properties for recognition of diacetyl were studied. The method employs the reaction of diacetyl with RBH, a colorless and non-fluorescent rhodamine B spiro form derivative to give a pink-colored fluorescent substance.
Li, Xiaohua, Duerkop, Axel, Wolfbeis, Otto S.   +2 more
openaire   +2 more sources