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Synthesis of fluorine-18 labeled 21-fluoroprogesterone

Steroids, 1977
21-Fluoroprogesterone has been synthesized by the nucleophilic displacement of the mesyl group of the 21-hydroxypregn-4-ene-3,20-dione 21-methanesulfonate by fluoride ion, as formed from the solvolysis of potassium fluoride in acetonitrile, using 18-Crown-6 as the catalyst.
L A, Spitznagle, C A, Marino
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Synthesis of the fluorine-18 labeled inhalation anesthetics

Applied Radiation and Isotopes, 1994
Fourteen compounds (fluoroalkanes and fluoroethers), including the two most utilized inhalation anesthetics Isoflurane (CF3CHClOCF2H) and Halothane (CF3CHBrCl), have been labeled with fluorine-18 via a facile 18F-for-19F exchange reaction. The compounds include ten inhalation anesthetics which span a ten-fold range in potency and four structurally ...
M R, Satter   +4 more
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[Fluorine-18 in radiopharmacy].

Annales pharmaceutiques francaises, 2008
Positron emission tomography (PET) is a recent and expanding functional nuclear imaging technique. Its extensive development is related to the radiophysical properties fluorine 18 (18F) (weak energy of positron, sufficiently long physical half-life) and to the simple production and labeling procedures for 18F.
V, de Beco, D, Le Bars, J-M, Scherrmann
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The value of fluorine-18 for scanning bone tumours

Clinical Radiology, 1969
The mechanisms of uptake of fluorine and strontium by normal as well as abnormal bone are described and the advantages of fluorine for scanning are emphasized. The scanning technique is discussed and a method for accurate reduction in size of the radiographic image to correspond exactly with that of the scan image is described.
C L, Harmer   +3 more
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Fluorine-18-fluorodeoxyglucose uptake in pneumonia.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998
Whole-body PET imaging with 18F-fluorodeoxyglucose (FDG) has been shown to be effective in distinguishing benign and malignant pulmonary disease. Mild elevations in FDG uptake with standardized uptake values (SUVs) less than 2.5 have been reported in benign lesions, including pneumonia.
Luketich, JD   +4 more
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A NEW SYNTHESIS OF FLUMAZENEL SUITABLE FOR FLUORINE-18 LABELING

Organic Preparations and Procedures International, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
BROGGINI, GIANLUIGI   +3 more
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SPECT imaging of fluorine-18.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1995
The objective of this work was to determine the potential clinical usefulness of SPECT to image 511-keV annihilation photons.A triple-headed gamma camera equipped with ultra-high-energy collimators was used to image 18F. Sensitivity measurements were carried out and the FWHM and FWTM were determined in air and for a unit-density scattering medium ...
P K, Leichner   +8 more
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A radiosynthesis of fluorine-18 fluoromisonidazole.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1989
A new preparation of [18F]fluoromisonidazole [1H-1-(3-[18F] fluoro-2-hydroxypropyl)-2-nitroimidazole] is presented as a two-step, two-pot reaction sequence. The method is useful for the production of 20-30 mCi quantities of this compound from [18F]fluoride, available in 40% radiochemical yield at end of bombardment (EOB) with a specific activity (nca ...
J R, Grierson   +4 more
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The standardisation of fluorine-18.

Australasian physical & engineering sciences in medicine, 1996
The Australian Nuclear Science and Technology Organisation (ANSTO) maintains and disseminates the Australian standards of activity measurement. The standards include all nuclear medicine gamma-emitters and pure positron emitters. Calibration factors for the ANSTO 4 pi ionisation chamber for pure positron emitters have been traditionally determined from
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Production of carrier-free fluorine-18

The International Journal of Applied Radiation and Isotopes, 1965
Abstract A rapid and effective procedure for the preparation of carrier-free fluorine-18 is described. The F 18 is produced by neutron irradiation of lithium carbonate and is separated by dissolving the material in acid and distilling off the hydrogen fluoride solution.
C.C. Thomas, J.A. Sondel, R.C. Kerns
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