Results 11 to 20 of about 152,276 (162)

Corrigendum: Optimized automated radiosynthesis of 18F-JNJ64413739 for purinergic ion channel receptor 7 (P2X7R) imaging in osteoporotic model rats [PDF]

open access: yesFrontiers in Pharmacology
Yingtong Lu   +9 more
doaj   +2 more sources

Hybridised production of technetium-99m and technetium-101 with fluorine-18 on a low-energy biomedical cyclotron

open access: yesEPJ Techniques and Instrumentation, 2023
New modes of production and supply of short-lived radioisotopes using accelerators are becoming attractive alternatives to the use of nuclear reactors. In this study, the use of a compact accelerator neutron source (CANS) was implemented to explore the ...
E. Johnstone   +2 more
semanticscholar   +1 more source

Simulating the Production of Medical Radioisotopes in a Fast Thorium-Cycle ADS with SERPENT

open access: yes, 2021
Radiopharmaceuticals are used in nuclear medicine for diagnostic or therapeutic acts. The short decay half-lives of medical radioisotopes, especially those used for diagnostics, imply that they should be produced continuously and transported as quickly ...
Ranjana Nath-M
semanticscholar   +1 more source

Rationalizing the Binding Modes of PET Radiotracers Targeting the Norepinephrine Transporter

open access: yesPharmaceutics, 2023
Purpose: A new PET radiotracer 18F-AF78 showing great potential for clinical application has been reported recently. It belongs to a new generation of phenethylguanidine-based norepinephrine transporter (NET)-targeting radiotracers. Although many efforts
Anna Tutov   +9 more
doaj   +1 more source

Advancements in Targeted Radiopharmaceuticals: Innovations in Diagnosis and Therapy for Enhanced Cancer Management. [PDF]

open access: yesChembiochem
Radiopharmaceuticals enable precise cancer diagnosis and targeted therapy by combining radioactive isotopes with carrier molecules. This review summarizes advances from 2014 to 2025, emphasizing probe design, click chemistry, novel targets, and nanodelivery systems.
Shaikh MS   +7 more
europepmc   +2 more sources

X-Ray fluorescence analysis of feldspars and silicate glass: effects of melting time on fused bead consistency and volatilisation [PDF]

open access: yes, 2011
Reproducible preparation of lithium tetraborate fused beads for XRF analysis of glass and mineral samples is of paramount importance for analytical repeatability.
Bell, Anthony   +11 more
core   +5 more sources

In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography [PDF]

open access: yes, 2008
The biodistribution profiles in mice of two pyrrole-imidazole polyamides were determined by PET. Pyrrole-imidazole polyamides are a class of small molecules that can be programmed to bind a broad repertoire of DNA sequences, disrupt transcription factor ...
Bergstr  m   +26 more
core   +3 more sources

Radiolabeling Strategies for Tumor-Targeting Proteinaceous Drugs

open access: yesMolecules, 2014
Owing to their large size proteinaceous drugs offer higher operative information content compared to the small molecules that correspond to the traditional understanding of druglikeness.
Grant Sugiura   +4 more
doaj   +1 more source

Dose Calibrator Linearity Testing: Radioisotope 99mTc or 18F? An Alternative for Reducing Costs in Nuclear Medicine Quality Control

open access: yesWorld Journal of Nuclear Medicine, 2015
Dose calibrator linearity testing is indispensable for evaluating the capacity of this equipment in measuring radioisotope activities at different magnitudes, a fundamental aspect of the daily routine of a nuclear medicine department, and with an impact ...
José Willegaignon   +7 more
doaj   +1 more source

Looking Inside the Human Body Using Radioactive Atoms

open access: yesFrontiers for Young Minds, 2022
Positron emission tomography (PET) is a method for taking pictures of a disease inside of a sick person’s body, without having to cut them open. In PET imaging, a radioactive chemical called a radiotracer is injected into a patient. All radiotracers have
M. G. O’Malley, J. Inkster
semanticscholar   +1 more source

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