Results 21 to 30 of about 3,535 (106)

Bioorthogonal Chemistry in Biomolecule Quantification: A Review of Reactions and Strategies

open access: yesChemistry – A European Journal, Volume 32, Issue 1, 2 January 2026.
This review summarizes the application of catalyst‐free bioorthogonal reactions: Staudinger ligation, strain promoted azide alkyne cycloaddition, inverse electron‐demand Diels–Alder, and 2‐cyanobenzothiazole cysteine condensation in the semi‐quantitative and quantitative analysis of biomolecules.
Mingze Yang, Shiqi Wang
wiley   +1 more source

Advancements in Targeted Radiopharmaceuticals: Innovations in Diagnosis and Therapy for Enhanced Cancer Management

open access: yesChemBioChem, Volume 27, Issue 1, January 2026.
Radiopharmaceuticals enable precise cancer diagnosis and targeted therapy by combining radioactive isotopes with carrier molecules. This review summarizes advances from 2014 to 2025, emphasizing probe design, click chemistry, novel targets, and nanodelivery systems.
Mohd Sayeed Shaikh   +7 more
wiley   +1 more source

Brain Incidentalomas in Positron Emission Tomography: A Systematic Literature Review and Meta‐Analysis

open access: yesClinical Neuroimaging, Volume 3, Issue 1, 2026.
ABSTRACT Background and Purpose Over the past decades, whole‐body PET‐CT scanning has undergone considerable innovation, with a considerable increase in clinical indications becoming a key diagnostic imaging method. Subsequently PET is contributing to the growth in imaging incidentaloma rates, including those of the brain, a critical functional tissue.
Feras Chehade   +7 more
wiley   +1 more source

Synthesis, Characterisation and Structural Analysis of Rhenium and Technetium Nitride Complexes With Tridentate Thiosemicarbazone‐Phenols and Phosphine Ligands: Potential Applications in Technetium‐99m Radiotracer Development

open access: yesBioinorganic Chemistry and Applications, Volume 2026, Issue 1, 2026.
The reactivity of two tridentate salicylthiosemicarbazones (H2L1 = 3‐methoxysalicylaldehyde thiosemicarbazone; H2L2 = 3‐methoxysalicylaldehyde N,N‐dimethyl‐thiosemicarbazone), with the [MV ≡ N]2+ core (M = Re, 99mTc), is here described, leading to the formation of heteroleptic complexes of the general composition [MN(L)P] (P = triphenylphosphine, PPh3;
Nicola Salvarese   +8 more
wiley   +1 more source

An Overview of Tracer Applications in the Upstream Petroleum Industry: A Focus on Enhanced Oil Recovery

open access: yesInternational Journal of Chemical Engineering, Volume 2026, Issue 1, 2026.
Tracers, recognized as vital technologies, enable precise monitoring of production processes, particularly in the context of enhanced oil recovery (EOR) projects. This study emphasizes tracers’ necessity as auxiliary tools for understanding reservoir characteristics, contributing to improved well productivity, reduced water production rates, and ...
Ali Akbari   +3 more
wiley   +1 more source

Sc(III) Complexes of Pyclen Derivative Ligands as Probes for Hypoxia: Synthesis, Chemical Characterization, 44Sc‐Radiolabeling, and Preclinical Assessment

open access: yesChemistry – A European Journal, Volume 31, Issue 72, December 23, 2025.
Hypoxia‐sensitive nitroimidazole‐functionalized pyclen derivatives were successfully synthesized and radiolabeled with 44Sc(III), affording stable and inert scandium complexes. Remarkable Sc(III)‐binding capabilities of the PC2A‐mono(amide) platform enabled excellent radiolabeling performance, with ≥92–99% yields and ≥99% radiochemical purity. MicroPET
Tibor Csupász   +9 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +28 more
wiley   +1 more source

The Development and Challenges of PET/MRI Dual‐Modality Imaging Probes—An Update

open access: yesJournal of Magnetic Resonance Imaging, Volume 62, Issue 5, Page 1245-1259, November 2025.
ABSTRACT The integration of Positron emission tomography (PET) with Magnetic resonance imaging (MRI) combines the functional imaging capabilities of PET with the high‐resolution anatomical detail of MRI, creating a synergistic platform for advanced diagnostic imaging and image‐guided therapies. Central to the success of this dual‐modality system is the
Maryam Sabbaghan   +5 more
wiley   +1 more source

Emerging applications of rare‐earth fluoride nanocrystals in medicine and biotechnologies

open access: yesResponsive Materials, Volume 3, Issue 4, November 2025.
Rare‐earth fluoride nanocrystals (REFNCs) exhibit high responsivity and can be used as multi‐modal agents in medicine and theranostics. This review summarizes recent advances in REFNCs, covering their synthesis, structures, luminescent properties, and applications in multi‐modal imaging and photodynamic therapy, highlighting their theranostic potential
Alain Tressaud   +3 more
wiley   +1 more source

Corrigendum: Optimized automated radiosynthesis of 18F-JNJ64413739 for purinergic ion channel receptor 7 (P2X7R) imaging in osteoporotic model rats

open access: yesFrontiers in Pharmacology
Yingtong Lu   +9 more
doaj   +1 more source

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