Results 21 to 30 of about 3,637 (104)

Exploring CPP Enhanced Hypoxia Targeting: An Approach Using Radiolabeled 2‐nitroimidazole TAT Conjugate

open access: yesDrug Development Research, Volume 87, Issue 1, February 2026.
ABSTRACT Mediated by their protein transduction domain, cell‐penetrating peptides (CPPs) have been widely explored for facilitating intracellular delivery of drugs and small molecules. In this study, a radiolabeled, 2‐nitroimidazole conjugated TAT (TAT ‐ transactivator of transcription) peptide was prepared and evaluated for targeting tumor hypoxia ...
Sweety Mittal   +4 more
wiley   +1 more source

Integrating Nuclear Medicine Services Into Health Care Systems in Low‐ and Middle‐Income Countries: A Review of Challenges and Innovations

open access: yesiRADIOLOGY, Volume 4, Issue 1, Page 3-12, February 2026.
Nuclear medicine is capable of solving noncommunicable diseases in LMICs but poses its own challenges. Research and investments are still needed. For nuclear medicine to answer the dynamics of noncommunicable diseases in the LMICs, it would have to overcome the high costs and regulations involved in this practice.
Biruk Demisse Ayalew   +12 more
wiley   +1 more source

Bioorthogonal Chemistry in Biomolecule Quantification: A Review of Reactions and Strategies

open access: yesChemistry – A European Journal, Volume 32, Issue 1, 2 January 2026.
This review summarizes the application of catalyst‐free bioorthogonal reactions: Staudinger ligation, strain promoted azide alkyne cycloaddition, inverse electron‐demand Diels–Alder, and 2‐cyanobenzothiazole cysteine condensation in the semi‐quantitative and quantitative analysis of biomolecules.
Mingze Yang, Shiqi Wang
wiley   +1 more source

Advancements in Targeted Radiopharmaceuticals: Innovations in Diagnosis and Therapy for Enhanced Cancer Management

open access: yesChemBioChem, Volume 27, Issue 1, January 2026.
Radiopharmaceuticals enable precise cancer diagnosis and targeted therapy by combining radioactive isotopes with carrier molecules. This review summarizes advances from 2014 to 2025, emphasizing probe design, click chemistry, novel targets, and nanodelivery systems.
Mohd Sayeed Shaikh   +7 more
wiley   +1 more source

Brain Incidentalomas in Positron Emission Tomography: A Systematic Literature Review and Meta‐Analysis

open access: yesClinical Neuroimaging, Volume 3, Issue 1, 2026.
ABSTRACT Background and Purpose Over the past decades, whole‐body PET‐CT scanning has undergone considerable innovation, with a considerable increase in clinical indications becoming a key diagnostic imaging method. Subsequently PET is contributing to the growth in imaging incidentaloma rates, including those of the brain, a critical functional tissue.
Feras Chehade   +7 more
wiley   +1 more source

Synthesis, Characterisation and Structural Analysis of Rhenium and Technetium Nitride Complexes With Tridentate Thiosemicarbazone‐Phenols and Phosphine Ligands: Potential Applications in Technetium‐99m Radiotracer Development

open access: yesBioinorganic Chemistry and Applications, Volume 2026, Issue 1, 2026.
The reactivity of two tridentate salicylthiosemicarbazones (H2L1 = 3‐methoxysalicylaldehyde thiosemicarbazone; H2L2 = 3‐methoxysalicylaldehyde N,N‐dimethyl‐thiosemicarbazone), with the [MV ≡ N]2+ core (M = Re, 99mTc), is here described, leading to the formation of heteroleptic complexes of the general composition [MN(L)P] (P = triphenylphosphine, PPh3;
Nicola Salvarese   +8 more
wiley   +1 more source

An Overview of Tracer Applications in the Upstream Petroleum Industry: A Focus on Enhanced Oil Recovery

open access: yesInternational Journal of Chemical Engineering, Volume 2026, Issue 1, 2026.
Tracers, recognized as vital technologies, enable precise monitoring of production processes, particularly in the context of enhanced oil recovery (EOR) projects. This study emphasizes tracers’ necessity as auxiliary tools for understanding reservoir characteristics, contributing to improved well productivity, reduced water production rates, and ...
Ali Akbari   +3 more
wiley   +1 more source

Sc(III) Complexes of Pyclen Derivative Ligands as Probes for Hypoxia: Synthesis, Chemical Characterization, 44Sc‐Radiolabeling, and Preclinical Assessment

open access: yesChemistry – A European Journal, Volume 31, Issue 72, December 23, 2025.
Hypoxia‐sensitive nitroimidazole‐functionalized pyclen derivatives were successfully synthesized and radiolabeled with 44Sc(III), affording stable and inert scandium complexes. Remarkable Sc(III)‐binding capabilities of the PC2A‐mono(amide) platform enabled excellent radiolabeling performance, with ≥92–99% yields and ≥99% radiochemical purity. MicroPET
Tibor Csupász   +9 more
wiley   +1 more source

88th Annual Meeting of the Meteoritical Society 2026: Abstracts

open access: yes
Meteoritics &Planetary Science, Volume 61, Issue S1, Page S48-S551, August 2026.
wiley   +1 more source

Corrigendum: Optimized automated radiosynthesis of 18F-JNJ64413739 for purinergic ion channel receptor 7 (P2X7R) imaging in osteoporotic model rats

open access: yesFrontiers in Pharmacology
Yingtong Lu   +9 more
doaj   +1 more source

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