Results 11 to 20 of about 6,505 (144)

Radiolabeling Strategies for Tumor-Targeting Proteinaceous Drugs

Molecules, 2014
Owing to their large size proteinaceous drugs offer higher operative information content compared to the small molecules that correspond to the traditional understanding of druglikeness.
Grant Sugiura, Helen Kühn, Max Sauter, Uwe Haberkorn, Walter Mier   +4 more
doaj   +1 more source

Dose Calibrator Linearity Testing: Radioisotope 99mTc or 18F? An Alternative for Reducing Costs in Nuclear Medicine Quality Control

World Journal of Nuclear Medicine, 2015
Dose calibrator linearity testing is indispensable for evaluating the capacity of this equipment in measuring radioisotope activities at different magnitudes, a fundamental aspect of the daily routine of a nuclear medicine department, and with an impact ...
José Willegaignon, Marcelo Sapienza, George Coura-Filho, Alexandre Garcez, Carlos Alves, Marissa Cardona, Ricardo Gutterres, Carlos Buchpiguel   +7 more
doaj   +1 more source

Folate-Based Radiotracers for PET Imaging—Update and Perspectives

Molecules, 2013
The folate receptor (FR) is expressed in many tumor types, among those ovarian and lung cancer. Due to the high FR affinity of folic acid, it has been used for targeting of FR-positive tumors, allowing specific delivery of attached probes to the ...
Cristina Müller
doaj   +1 more source

Development of PDT/PET theranostics: synthesis and biological evaluation of an ¹⁸F-radiolabeled water soluble porphyrin [PDF]

, 2015
Synthesis of the first water-soluble porphyrin radiolabeled with fluorine-18 is described: a new molecular theranostic agent which integrates the therapeutic selectivity of photodynamic therapy (PDT) with the imaging efficacy of positron emission ...
Allott, Louis, Archibald, Stephen J., Boyle, Ross W., Bryden, Francesca, Cawthorne, Chris, Domarkas, Juozas, Entract, Guy M., Savoie, Huguette   +7 more
core   +1 more source

Radiogenic and Muon-Induced Backgrounds in the LUX Dark Matter Detector [PDF]

, 2014
The Large Underground Xenon (LUX) dark matter experiment aims to detect rare low-energy interactions from Weakly Interacting Massive Particles (WIMPs).
Akerib, D. S., Araujo, H. M., Bai, X., Bailey, A. J., Balajthy, J., Bernard, E., Bernstein, A., Bradley, A., Byram, D., Cahn, S. B., Carmona-Benitez, M. C., Chan, C., Chapman, J. J., Chiller, A. A., Chiller, C., Coffey, T., Currie, A., de Viveiros, L., Dobi, A., Dobson, J., Druszkiewicz, E., Edwards, B., Faham, C. H., Fiorucci, S., Flores, C., Gaitskell, R. J., Gehman, V. M., Ghag, C., Gibson, K. R., Gilchriese, M. G. D., Hall, C., Hertel, S. A., Horn, M., Huang, D. Q., Ihm, M., Jacobsen, R. G., Kazkaz, K., Knoche, R., Larsen, N. A., Lee, C., Lindote, A., Lopes, M. I., Malling, D. C., Mannino, R., McKinsey, D. N., Mei, D. -M., Mock, J., Moongweluwan, M., Morad, J., Murphy, A. St. J., Nehrkorn, C., Nelson, H., Neves, F., O'Sullivan, K., Ott, R. A., Pangilinan, M., Parker, P. D., Pease, E. K., Pech, K., Phelps, P., Reichhart, L., Shutt, T., Silva, C., Solovov, V. N., Sorensen, P., Sumner, T. J., Szydagis, M., Taylor, D., Tennyson, B., Tiedt, D. R., Tripathi, M., Uvarov, S., Verbus, J. R., Walsh, N., Webb, R., White, J. T., Witherell, M. S., Wolfs, F. L. H., Woods, M., Zhang, C.   +79 more
core   +2 more sources

Comparison of the efficacy of biodegradable and non-biodegradable scintillation liquids on the counting of tritium- and [14C]-labeled compounds [PDF]

, 2003
The widespread use of ³H and 14C in research has generated a large volume of waste mixed with scintillation liquid, requiring an effective control and appropriate storage of liquid radioactive waste.
Godinho, Rosely Oliveira, Mattos, M.f.s.s., Medeiros, Regina Bitelli   +2 more
core   +3 more sources

Stable BF2 Boracycles as Versatile Reagents for Selective Ortho C–H Functionalization

Angewandte Chemie, Volume 138, Issue 8, 16 February 2026.
We report a robust, metal‐free and scalable synthesis of stable BF2 boracycles via directed ortho CH borylation, delivering isolable, shelf‐stable reagents without chromatographic purification. These BF2 boracycles exhibit unique and tunable reactivity, enabling highly selective ipso‐functionalization across a broad range of transformations.
Ganesh H. Shinde, Jonatan Babiker, Michelle Mebrahtu, Anaïs Prigent, Gauthier Foucras, Yogesh N. Aher, Francoise M. Amombo Noa, Magnus J. Johansson, Janez Košmrlj, Ross D. Jansen‐van Vuuren, Thomas Cailly, Henrik Sundén   +11 more
wiley   +2 more sources

Optimized automated radiosynthesis of 18F-JNJ64413739 for purinergic ion channel receptor 7 (P2X7R) imaging in osteoporotic model rats

Frontiers in Pharmacology
ObjectiveTo optimize the automated radiosynthesis of the purinergic ion channel receptor 7 (P2X7R) imaging agent 18F-JNJ64413739 and evaluate its potential for brain imaging in osteoporotic model rats.MethodsA more electron-deficient nitropyridine was ...
Yingtong Lu, Yan Cui, Lu Hou, Yuanfang Jiang, Jingjie Shang, Lu Wang, Hao Xu, Weijian Ye, Yang Qiu, Bin Guo   +9 more
doaj   +1 more source

Évolution des cancers de l’œsophage : impact de la stratégie thérapeutique [PDF]

, 2013
PURPOSE: To assess the outcome of esophageal cancer according to therapeutic strategy. PATIENTS AND METHODS: One-hundred and twenty patients with esophageal cancer treated by an association of radiotherapy and chemotherapy and possibly surgery, between ...
A. Hamy, A. Paumier, A.L. Poirier, D. Rousseau, F. Denis, M.A. Mahé, N. Mesgouez-Nebout, O. Capitain, P. Cellier, S. Girault   +9 more
core   +4 more sources

Carbon‐14 Perovskite Betavoltaics Reach Record 10.79% Efficiency

Carbon Energy, EarlyView.
A perovskite‐based betavoltaic cell incorporating carbon‐14 nanoparticles and formamidinium lead iodide achieves a record energy conversion efficiency of 10.79%. The device design enhances charge generation through an electron avalanche multiplication mechanism.
Hong Soo Kim, Ryan Rhee, Junho Lee, Muhammad Bilal Naseem, Jung Hwan Lee, Jong Hyeok Park, Su‐Il In   +6 more
wiley   +1 more source