Development of PDT/PET theranostics: synthesis and biological evaluation of an ¹⁸F-radiolabeled water soluble porphyrin [PDF]
, 2015 Synthesis of the first water-soluble porphyrin radiolabeled with fluorine-18 is described: a new molecular theranostic agent which integrates the therapeutic selectivity of photodynamic therapy (PDT) with the imaging efficacy of positron emission ...
Allott, Louis +7 more
core +1 more source
Comparison of the efficacy of biodegradable and non-biodegradable scintillation liquids on the counting of tritium- and [14C]-labeled compounds [PDF]
, 2003 The widespread use of ³H and 14C in research has generated a large volume of waste mixed with scintillation liquid, requiring an effective control and appropriate storage of liquid radioactive waste.
Godinho, Rosely Oliveira +2 more
core +3 more sources
Direct arene C–H fluorination with 18F− via organic photoredox catalysis
Science, 2019 A metal-free route to PET probes Positron emission tomography (PET) is a widely used imaging technique for medical diagnostics and pharmaceutical development.
Wei Chen +8 more
semanticscholar +1 more source
Frontiers in PharmacologyObjectiveTo optimize the automated radiosynthesis of the purinergic ion channel receptor 7 (P2X7R) imaging agent 18F-JNJ64413739 and evaluate its potential for brain imaging in osteoporotic model rats.MethodsA more electron-deficient nitropyridine was ...
Yingtong Lu +9 more
doaj +1 more source
Trace Analysis of Marine Organisms: A Comparison of Activation Analysis and Conventional Methods [PDF]
, 1959 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/109766/1/lno1959440398 ...
Fukai, Rinnosuke, Meinke, W. W.
core +1 more source
Évolution des cancers de l’œsophage : impact de la stratégie thérapeutique [PDF]
, 2013 PURPOSE: To assess the outcome of esophageal cancer according to therapeutic strategy. PATIENTS AND METHODS: One-hundred and twenty patients with esophageal cancer treated by an association of radiotherapy and chemotherapy and possibly surgery, between ...
A. Hamy +9 more
core +4 more sources
Why are we failing to implement imaging studies with radiolabelled new molecular entities in early oncology drug development? [PDF]
, 2014 In early drug development advanced imaging techniques can help with progressing new molecular entities (NME) to subsequent phases of drug development and thus reduce attrition.
Lahn, M +3 more
core +3 more sources
Stable BF2 Boracycles as Versatile Reagents for Selective Ortho C–H Functionalization
Angewandte Chemie International Edition, EarlyView.We report a robust, metal‐free and scalable synthesis of stable BF2 boracycles via directed ortho CH borylation, delivering isolable, shelf‐stable reagents without chromatographic purification. These BF2 boracycles exhibit unique and tunable reactivity, enabling highly selective ipso‐functionalization across a broad range of transformations.
Ganesh H. Shinde +11 more
wiley +1 more source
Carbon‐14 Perovskite Betavoltaics Reach Record 10.79% Efficiency
Carbon Energy, EarlyView.A perovskite‐based betavoltaic cell incorporating carbon‐14 nanoparticles and formamidinium lead iodide achieves a record energy conversion efficiency of 10.79%. The device design enhances charge generation through an electron avalanche multiplication mechanism.
Hong Soo Kim +6 more
wiley +1 more source
Veterinary and Comparative Oncology, EarlyView.ABSTRACT Lymph node (LN) metastasis has been associated with shorter survival times in dogs with mast cell tumour (MCT), and treatment of metastatic LN with lymphadenectomy or irradiation has been demonstrated to improve outcomes. Identification of metastatic LN in dogs with MCT is therefore of both prognostic and therapeutic significance.
Alison C. Williams +5 more
wiley +1 more source