Results 31 to 40 of about 152,276 (162)

Exploring CPP Enhanced Hypoxia Targeting: An Approach Using Radiolabeled 2‐nitroimidazole TAT Conjugate

open access: yesDrug Development Research, Volume 87, Issue 1, February 2026.
ABSTRACT Mediated by their protein transduction domain, cell‐penetrating peptides (CPPs) have been widely explored for facilitating intracellular delivery of drugs and small molecules. In this study, a radiolabeled, 2‐nitroimidazole conjugated TAT (TAT ‐ transactivator of transcription) peptide was prepared and evaluated for targeting tumor hypoxia ...
Sweety Mittal   +4 more
wiley   +1 more source

Informetrics on accidents and trauma [PDF]

open access: yes, 1998
MEDLINE database has been analysed for 1995-97 on index Accidents and Trauma. Publications output has been classified year-wise country-wise, journal-wise and other fine structure characteristics have been found.
Kadam, S. N., Kalyane, V. L.
core  

Radioactive Ion Sources

open access: yes, 2014
This chapter provides an overview of the basic requirements for ion sources designed and operated in radioactive ion beam facilities. The facilities where these sources are operated exploit the isotope separation online (ISOL) technique, in which a ...
Stora, T.
core   +1 more source

Bioorthogonal Chemistry in Biomolecule Quantification: A Review of Reactions and Strategies

open access: yesChemistry – A European Journal, Volume 32, Issue 1, 2 January 2026.
This review summarizes the application of catalyst‐free bioorthogonal reactions: Staudinger ligation, strain promoted azide alkyne cycloaddition, inverse electron‐demand Diels–Alder, and 2‐cyanobenzothiazole cysteine condensation in the semi‐quantitative and quantitative analysis of biomolecules.
Mingze Yang, Shiqi Wang
wiley   +1 more source

DOES PET/CT WITH 18F-FLUOROESTRADIOL (18F-FES) CONTRIBUTE TO THE ASSESSMENT OF BREAST CANCER COMPARED TO FLUORINE-2-D-DEOXYGLUCOSE (18F-FDG)?

open access: yesHematology, Transfusion and Cell Therapy
Introduction/Justification: While fluorine-2-D-deoxyglucose (18F-FDG) PET/CT is commonly used in the assessment of breast cancer, it has limitations, such as its inability to distinguish it from inflammatory and infectious conditions.
Bruno Russiano de Oliveira Boeno   +4 more
doaj   +1 more source

Clouds, airplanes, trucks and people: carrying radioisotopes to and across Mexico [PDF]

open access: yes, 2015
The aim of this paper is to describe the early stages of Mexican nuclearization that took place in contact with radioisotopes. This history requires a multilayered narrative with an emphasis in North-South asymmetric relations, and in the value of ...
Mateos, Gisela, Suárez-Díaz, Edna
core   +4 more sources

Sc(III) Complexes of Pyclen Derivative Ligands as Probes for Hypoxia: Synthesis, Chemical Characterization, 44Sc‐Radiolabeling, and Preclinical Assessment

open access: yesChemistry – A European Journal, Volume 31, Issue 72, December 23, 2025.
Hypoxia‐sensitive nitroimidazole‐functionalized pyclen derivatives were successfully synthesized and radiolabeled with 44Sc(III), affording stable and inert scandium complexes. Remarkable Sc(III)‐binding capabilities of the PC2A‐mono(amide) platform enabled excellent radiolabeling performance, with ≥92–99% yields and ≥99% radiochemical purity. MicroPET
Tibor Csupász   +9 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +28 more
wiley   +1 more source

The Development and Challenges of PET/MRI Dual‐Modality Imaging Probes—An Update

open access: yesJournal of Magnetic Resonance Imaging, Volume 62, Issue 5, Page 1245-1259, November 2025.
ABSTRACT The integration of Positron emission tomography (PET) with Magnetic resonance imaging (MRI) combines the functional imaging capabilities of PET with the high‐resolution anatomical detail of MRI, creating a synergistic platform for advanced diagnostic imaging and image‐guided therapies. Central to the success of this dual‐modality system is the
Maryam Sabbaghan   +5 more
wiley   +1 more source

Emerging applications of rare‐earth fluoride nanocrystals in medicine and biotechnologies

open access: yesResponsive Materials, Volume 3, Issue 4, November 2025.
Rare‐earth fluoride nanocrystals (REFNCs) exhibit high responsivity and can be used as multi‐modal agents in medicine and theranostics. This review summarizes recent advances in REFNCs, covering their synthesis, structures, luminescent properties, and applications in multi‐modal imaging and photodynamic therapy, highlighting their theranostic potential
Alain Tressaud   +3 more
wiley   +1 more source

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