Results 11 to 20 of about 117,479 (219)

Tuning the Anti(myco)bacterial Activity of 3-Hydroxy-4-pyridinone Chelators through Fluorophores

Pharmaceuticals, 2018
Controlling the sources of Fe available to pathogens is one of the possible strategies that can be successfully used by novel antibacterial drugs. We focused our interest on the design of chelators to address Mycobacterium avium infections.
Maria Rangel, Tânia Moniz, André M. N. Silva, Andreia Leite   +3 more
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A review of the synthetic strategies for the development of BODIPY dyes for conjugation with proteins.

Orbital: The Electronic Journal of Chemistry, 2013
Conjugation of fluorophores to proteins is fundamental to several biotechnological applications and in the last decades boron-dipyrromethene (BODIPY) dyes started to be used in this field.
Lucas C. D. Rezende, Flavio S. Emery
doaj   +1 more source

Red-Shift (2-Hydroxyphenyl)-Benzothiazole Emission by Mimicking the Excited-State Intramolecular Proton Transfer Effect

Frontiers in Chemistry, 2021
Novel strategies to optimize the photophysical properties of organic fluorophores are of great significance to the design of imaging probes to interrogate biology.
Yong Ren, Lei Zhou, Lei Zhou, Xin Li
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BODIPY-based dye for no-wash live-cell staining and imaging

BioTechniques, 2017
In nonpolar solvents, hydrophobic organic fluorophores often show bright fluorescence, whereas in polar media, they usually suffer from aggregation-caused quenching (ACQ).
Alexey A. Pakhomov, Igor E. Deyev, Natalia M. Ratnikova, Stepan P. Chumakov, Veronika B. Mironiuk, Yuriy N. Kononevich, Aziz M. Muzafarov, Vladimir I. Martynov   +7 more
doaj   +1 more source

Modified in situ Hybridization Chain Reaction Using Short Hairpin DNAs

Frontiers in Molecular Neuroscience, 2020
The visualization of multiple gene expressions in well-preserved tissues is crucial for the elucidation of physiological and pathological processes. In situ hybridization chain reaction (HCR) is a method to visualize specific mRNAs in diverse organisms ...
Yousuke Tsuneoka, Hiromasa Funato, Hiromasa Funato   +2 more
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Use of IHF-QD Microscopic Analysis for the Detection of Food Allergenic Components: Peanuts and Wheat Protein

Foods, 2020
The aim of the study was to analytically evaluate quantum dots in immunohistofluorescence (IHF-QD) microscopic imaging as detectors of food allergens—peanut and wheat.
Ludmila Kalčáková, Bohuslava Tremlová, Matej Pospiech, Martin Hostovský, Dani Dordević, Zdeňka Javůrková, Hana Běhalová, Marie Bartlová   +7 more
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Bleaching‐Resistant Super‐Resolution Fluorescence Microscopy

Advanced Science, 2022
Photobleaching is the permanent loss of fluorescence after extended exposure to light and is a major limiting factor in super‐resolution microscopy (SRM) that restricts spatiotemporal resolution and observation time.
Jiwoong Kwon, Mohamed Saleh Elgawish, Sang‐Hee Shim   +2 more
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FRET Based Biosensor: Principle Applications Recent Advances and Challenges

Diagnostics, 2023
Förster resonance energy transfer (FRET)-based biosensors are being fabricated for specific detection of biomolecules or changes in the microenvironment.
Awadhesh Kumar Verma, Ashab Noumani, Amit K. Yadav, Pratima R. Solanki   +3 more
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The Impact of Photobleaching on Microarray Analysis

Biology, 2015
DNA-Microarrays have become a potent technology for high-throughput analysis of genetic regulation. However, the wide dynamic range of signal intensities of fluorophore-based microarrays exceeds the dynamic range of a single array scan by far, thus ...
Marcel von der Haar, John-Alexander Preuß, Kathrin von der Haar, Patrick Lindner, Thomas Scheper, Frank Stahl   +5 more
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BOPAM’s Bright and Dark Excited States: Insight from Structural, Photophysical, and Quantum Chemical Investigations

Molecules
BOPAM exhibits high fluorescence quantum yields, along with exceptional photostability, rendering it a promising platform for applications as fluorescence sensors.
Kexin Yu, Thanh Chung Pham, Jianjun Huang, Yixuan Li, Luc Van Meervelt, Mark Van der Auweraer, Daniel Escudero, Wim Dehaen   +7 more
doaj   +1 more source