Results 31 to 40 of about 132,621 (262)

Sequence-Specific Biosensing of DNA Target through Relay PCR with Small-Molecule Fluorophore

, 2016
Polymerase chain reaction coupled with signal generation offers sensitive recognition of target DNA sequence; however, these procedures require fluorophore-labeled oligonucleotide probes and high-tech equipment to achieve high specificity.
Yasmeen, A, Du, F, Huang, X, Zhao, YY, Cui, X, Chen, HD, Tang, Z (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu 610041, Peoples R China., Dong, J, Tang, Z   +8 more
core   +1 more source

Selectivity of a bromoacridine-containing fluorophore for triplex DNA [PDF]

, 2021
Fluorophore 1,8-naphthilamide was linked to 2-bromoacridine through an ethylenediamine spacer using a succinct synthetic route to give a bromoacridine-linked bifunctional fluorophore conjugate for the detection of triplex DNA.
Sharma, Sanjeev, Fraser, William
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Fluorophore-Induced Plasmonic Current in Metal Nanoparticle Island Films

, 2020
Fluorophore-induced plasmonic current is generated when an excited fluorophore in proximity to a metal nanoparticle island film non-radiatively transfers energy to the metal, inducing a measurable change in electrical current through the film.
Moskowitz, Joshua
core   +1 more source

Inactivation of acetylcholinesterase by various fluorophores [PDF]

Journal of Enzyme Inhibition and Medicinal Chemistry, 2009
The inhibition of recombinant mouse acetylcholinesterase (rMAChE) and electric eel acetylcholinesterase (EEAChE) by seven, structurally different chromophore-based (dansyl, pyrene, dabsyl, diethylamino- and methoxycoumarin, Lissamine rhodamine B, and Texas Red) propargyl carboxamides or sulfonamides was studied.
Lilu, Guo, Alirica I, Suarez, Charles M, Thompson   +2 more
openaire   +2 more sources

DNA‐Templated 2D Heterostructures as Phototriggered Dynamic Nanohybrids: From Releasing Molecular Loads to Controlling Enzyme Biocatalytic Function

Advanced Functional Materials, EarlyView.
DNA strands are employed both as dynamic linkers and nanoscale templates for the integration of Ag2S nanoparticles on MoS2, which in turn imparted photothermal responsiveness; this feature permits the selective cargo (fluorophore, quantum dots or an enzyme) release from the MoS2 surface in response to local heat induced by light irradiation.
Kai Chen, Haosen Miao, Weiying Hong, Matteo Palma   +3 more
wiley   +1 more source

Synthesis and use of fluorophore-tagged antimalarials

, 2012
This invention includes a fluorophore-tagged antimalarial represented by the following structural formula (1) or a salt thereof. This invention relates to the synthesis of fluorophore-tagged antimalarials and describes the synthesis of a fluorophore ...
Martin Lear (17161933), Kevin SA WA Tan (18250699)   +1 more
core   +1 more source

Small molecule fluorophore uptake and distribution in tumor explants (TE).

, 2020
Resected xenograft tissue grown as explants were incubated for 48-hour with 500 nM of nonreactive fluorophore representing different chemical scaffolds: AF488, AF546, AF647 and Atto680. A. Representative images from fresh frozen samples, shown normalized
Lei Wang (6656), Summer L. Gibbs (8491464), Allison Solanki (514184), Diana King (8491458), Guillaume Thibault (8491461)   +4 more
core   +1 more source

Packed Hydrogel Microfibers as Scaffolds Supporting Dynamic Cellular Behavior and Biomaterial Inks in 3D Printing

Advanced Healthcare Materials, EarlyView.
Packed hydrogel microfiber (PHM) materials consist of flexible and high aspect ratio hydrogel components that, as a bulk material, are simultaneously mechanically robust and dynamic. Cells cultured in or on PHM scaffolds can be influenced by topographical cues or interact with a dynamic environment that permits cell spreading and multicellular ...
M. Gregory Grewal, Remington M. Martinez, Georgia T. Helein, Montserrath G. Ibarra Rivera, Rodolfo Martinez Jr., Jenna L. Sumey, Steven R. Caliari, Christopher B. Highley   +7 more
wiley   +1 more source