Results 51 to 60 of about 174,614 (242)
Prognostic factors for patients with esophageal cancer who achieve pathological complete response in the primary tumor after upfront chemotherapy or chemoradiotherapy
Annals of Gastroenterological Surgery, EarlyView.Male gender and pathological lymph node metastasis are independent poor prognostic factors in patients with esophageal cancer who receive upfront treatment followed by surgery and achieved pathological complete response of the primary tumor. Among patients without pathological lymph node metastasis, the upfront chemotherapy group showed significantly ...Masaaki Motoori, Koji Tanaka, Hiroshi Miyata, Makoto Yamasaki, Osamu Shiraishi, Atsushi Takeno, Tomoki Makino, Keijiro Sugimura, Takushi Yasuda, Yuichiro Doki +9 morewiley +1 more sourcePerioperative outcomes of esophagectomy after doublet versus docetaxel‐based triplet neoadjuvant chemotherapy in older patients: A nationwide inpatient database study in Japan
Annals of Gastroenterological Surgery, EarlyView.In this nationwide inpatient database study of 5229 patients aged 70–79 years who underwent esophagectomy for cancer after neoadjuvant chemotherapy, overlap propensity score weighting analysis showed that neoadjuvant docetaxel‐based triplet regimen (docetaxel, cisplatin, and 5‐fluorouracil) was not associated with a higher incidence of perioperative ...Yuki Hirano, Takaaki Konishi, Hidehiro Kaneko, Satoru Matsuda, Hirofumi Kawakubo, Yuya Kimura, Hiroki Matsui, Kiyohide Fushimi, Hiroyuki Daiko, Osamu Itano, Hideo Yasunaga, Yuko Kitagawa +11 morewiley +1 more sourceClinical role of intraperitoneal chemotherapy in patients with pancreatic ductal adenocarcinoma concomitant with occult peritoneal dissemination: A multicenter retrospective study
Annals of Gastroenterological Surgery, EarlyView.The effectiveness of intraperitoneal chemotherapy using paclitaxel (i.p.‐PTX) in pancreatic ductal adenocarcinoma (PDAC) patients with peritoneal dissemination remains elusive. This study indicated that the i.p.‐PTX therapy may improve survival in selected patients with PDAC, in particular those with occult peritoneal dissemination.Tomohisa Yamamoto, Toshio Shimokawa, Masamichi Hayashi, Masamichi Mizuma, Katsuhisa Hirano, Atsushi Oba, Toshimichi Asano, Hideyo Miyato, Makoto Yoshida, Ippei Matsumoto, Yasunari Kawabata, Katsunori Sakamoto, Fuyuhiko Motoi, Shigeto Ishii, Yuki Homma, Hiromitsu Maehira, Yutaro Matsunaga, Tetsuya Ikemoto, Masafumi Nakamura, Yuko Mataki, Tsuyoshi Notake, Keiichi Akahoshi, Hideki Takami, So Yamaki, Daisuke Hashimoto, Yasutoshi Kimura, Satoshi Hirano, Yosuke Inoue, Tsutomu Fujii, Michiaki Unno, Yasuhiro Kodera, Joji Kitayama, Sohei Satoi, the Study Group of Pancreatic Ductal Adenocarcinoma with Peritoneal Dissemination +33 morewiley +1 more sourcePhase II trial of preoperative radiochemotherapy with concurrent bevacizumab, capecitabine and oxaliplatin in patients with locally advanced rectal cancer [PDF]
, 2013 Background: Preoperative radiochemotherapy (RCT) with 5-FU or capecitabine is the standard of care for patients with locally advanced rectal cancer (LARC). Preoperative RCT achieves pathological complete response rates (pCR) of 10-15%.Arnold, Dirk, Dellas, Kathrin, Dunst, Jürgen, Engel, Erik, Höhler, Thomas, Reese, Thomas, Richter, Michael, Rödel, Claus, Wagner, Wolfgang, Würschmidt, Florian +9 morecore +1 more sourceSingle-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy [PDF]
, 2013 Uracil in DNA is an important cause of mutagenesis. SMUG1 is a uracil DNA glycosylase that removes uracil through base excision repair. SMUG1 also processes radiation induced oxidative base damage as well as 5-fluorouracil incorporated into DNA during Abdel-Fatah, TMA, Agarwal, D, Albarakati, N, Ball, G, Bowell, L, Chan, S, Ellis, IO, Hawkes, C, Madhusudan, S, Moseley, P +9 morecore +1 more sourceDoes surgical intervention contribute to survival for patients with para‐aortic lymph node metastasis from colorectal cancer?
Annals of Gastroenterological Surgery, EarlyView.Overall survival of patients who underwent surgical resection was significantly better compared to that of patients who underwent chemotherapy without surgical resection. These results highlight the benefit of surgical intervention to survival for patients with isolated para‐aortic lymph node metastasis or with resectable liver metastasis.Akira Ouchi, Koji Komori, Sono Ito, Yusuke Kinugasa, Soichiro Ishihara, Akio Shiomi, Yukihide Kanemitsu, Takeshi Suto, Hiroki Takahashi, Yoichi Ajioka, on behalf of the study group for PALNM projected by JSCCR, Akinobu Furutani, Akira Hirata, Atsushi Ishibe, Eiji Sunami, Heita Ozawa, Hideki Ueno, Hideyuki Ishida, Hiroyuki Egi, Ichiro Takemasa, Jun Watanabe, Junichiro Hiro, Kay Uehara, Kazushige Kawai, Koya Hida, Manabu Shiozawa, Masaaki Ito, Masakatsu Numata, Masanori Hotchi, Masaya Hiyoshi, Masayuki Ohue, Michio Itabashi, Ryo Inada, Shuntaro Nagai, Takaya Kobatake, Takeshi Kato, Tomohiro Yamaguchi, Yasumasa Takii, Yasumitsu Hirano, Yoshihiro Kakeji +39 morewiley +1 more sourceInterventions for the treatment of oral cavity and oropharyngeal cancer:chemotherapy [PDF]
, 2010 <b>Background:</b> Oral cavity and oropharyngeal cancers are frequently described as part of a group of oral cancers or head and neck cancer. Treatment of oral cavity cancer is generally surgery followed by radiotherapy, whereas oropharyngeal Abdel Wahab, Abele, Adelstein, Adelstein, Adelstein, Andreadis, Andres, Anonymous, Anonymous, Ansfield, Arcangeli, Aref, Attner, Bachaud, Bakowski, Bensadoun, Berger, Bernier, Bernier, Bezwoda, Biakhov, Biakhov, Bitter, Bitter, Blasio, Boidi, Bolla, Bonner, Bourhis, Bourhis, Bradley, Brigham, Brizel, Browman, Browman, Browman, Browman, Browman, Browman, Browman, Browman, Brunin, Brunin, Budach, Budach, Buentzel, Buentzel, Buntzel, Buntzel, Buntzel, Buntzel, Cachin, Calais, Calais, Calais, Calais, Calais, Calais, Caponigro, Caponigro, Cappelaere, Cappelaere, Carugati, Chassagne, Chauvergne, Chauvergne, Clavel, Clifford, Coates, Coninx, Coninx, Conway, Cooper, Corey, Corvo, Corvo, Corvo, Crispino, Cruz, Cummings, Dalley, Datta, Day, DeConti, Denis, Denis, Depondt, Dobrowsky, Dobrowsky, Domenge, Domenge, Domenge, Domenge, Ebeling, Eschwege, Eschwege, Ezra, Faggiano, Fakhry, Fanucchi, Fazekas, Fazekas, Fety, Fety, Fonseca, Forastiere, Fountzilas, Fountzilas, Fu, Fu, Fujii, Fujii, Funk, Furukawa, Gabriele, Gasparini, Gedouin, Gedouin, Gehanno, Gibson, Gladkov, Gollin, Gonzalez-Larriba, Grandi, Grau, Grau, Grau, Griem, Gupta, Gupta, Haas, Haas, Haas, Haddad, Haddadin, Haffty, Haffty, Haffty, Haffty, Haffty, Hafty, Handa, Harari, Hasegawa, Haselow, Henk, Heyden, Heyden, Heyden, Heyden, Heyden, Heyden, Hitt, Holoye, Holoye, Homma, Hong, Hughes, Huguenin, Hussey, Jacobs, Jain, Jaulerry, Jeremic, Jeremic, Jeremic, Jeremic, Jeremic, Jones, Jortay, Kaneda, Kapstad, Kapstad, Katori, Keegan, Knowlton, Kotani, Kramer, Krishnamurthi, Kumar, Laccourreye, Lam, Laramore, Lavertu, Le, Le, Lee, Lewin, Licitra, Lim, Lippman, Lo, Lopes, Luboinski, Macfarlane, Magno, Maipang, Mantovani, Marechal, Martin, Martin, Martin, Mazeron, McGurk, Mechl, Merlano, Merlano, Merlano, Merlano, Merlano, Merlano, Mohr, Monson, Morita, Morton, Morton, Nervi, Nissenbaum, O'Connor, Olasz, Olasz, Oliver, Oliver, Olmi, Olmi, Paccagnella, Paccagnella, Panis, Papac, Parkin, Parmar, Partridge, Parvinen, Patel, Pavitt, Pearlman, Pentenero, Petrovich, Petrovich, Phillips, Pignon, Pinnaro, Pinto, Platzer, Posner, Price, Prévost, Racadot, Rao, Rao, Rapoport, Rasch, Rasch, Rentschler, Richard, Richard, Richard, Richard, Rischin, Rischin, Rischin, Rodrigo, Ruo Redda, Ryerson, Salvajoli, Sanchiz, Sanguineti, Schildhauer, Schildhauer, Schroder, Schuller, Schuller, Schuller, Sealy, Segura, Semrau, Shah, Shanta, Shaw, Shetty, Siodlak, Smid, Smid, Soo, Specenier, Staar, Staar, Stefani, Stefani, Stell, Stell, Sturgis, Suwinski, Szabo, Szpirglas, Szpirglas, Szpirglas, Taylor, Taylor, Taylor, Tejedor, Tepmongkol, Tobias, Tobias, Tobias, Tobias, Toohill, Toohill, Tsukuda, Tsukuda, Valverde, Vecchia, Vega, Vermund, Veronesi, Volling, Volling, Volling, Weissberg, Weissberg, Weissberg, Weissberg, Weissberg, Weissler, Wendt, Wendt, WHO, Woods, Woods, Woods, Woolgar, Yoshino, Yoshino, Zakotnik, Zakotnik, Zakotnik, Zorat, Zorat +337 morecore +6 more sourcesPrognostic Impact of Bone Mineral Density Reduction During Neoadjuvant Chemotherapy (NAC) in Patients Undergoing NAC Followed by Esophagectomy for Esophageal Cancer
Annals of Gastroenterological Surgery, EarlyView.The association between BMD reduction during NAC and the worse prognosis remains unknown, although NAC followed by esophagectomy is a standard treatment for advanced ESCC. This study appeared that BMD massive reduction was an independent prognostic factor on OS (HR, 3.30; 95% confidence interval [CI], 1.69–6.55) and RFS (HR, 2.08; 95% CI, 1.19–3.63 ...Kazuhide Sato, Keita Takahashi, Yoshitaka Ishikawa, Naoko Fukushima, Takahiro Masuda, Takanori Kurogochi, Masami Yuda, Akira Matsumoto, Kazuto Tsuboi, Yuichiro Tanishima, Fumiaki Yano, Ken Eto +11 morewiley +1 more sourceSurvival Outcomes of Esophageal Squamous Cell Carcinoma Patients Who Underwent Salvage Esophagectomy: A Literature Review and Results From Two High‐Volume Centers
Annals of Gastroenterological Surgery, EarlyView.This study aimed to investigate survival outcomes, the efficacy of lymph node (LN) dissection, and recurrence patterns in 69 patients who underwent R0 salvage surgery for esophageal squamous cell carcinoma. Of note, abdominal LN metastases had a negative impact on survival in our series.Kotaro Sugawara, Koichi Yagi, Takashi Fukuda, Shoh Yajima, Daiji Oka, Yoshiyuki Miwa, Shuichiro Oya, Asami Okamoto, Raito Asaoka, Yoshifumi Baba +9 morewiley +1 more source