Results 51 to 60 of about 38,009 (171)

Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines

Environmental Toxicology and Chemistry, EarlyView.
Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz, Krittika Mittal, Na'im Temlock, Jessica Head, Niladri Basu   +4 more
wiley   +1 more source

Alleviation of the hepatotoxicity effects of fluoxetine using acetylcysteine with the royal jelly in rats

Egyptian Liver Journal
Background Fluoxetine is commonly used as the initial option for depressive symptoms and other neurological disorders. The repeated use of fluoxetine was related to hepatotoxicity and persistent liver disease.
Azad Hayal Nahy, Manal AbdulKhaliq Ibrahim, Manal N. Alhayder   +2 more
doaj   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Serotonin reuptake inhibitors improve muscle stem cell function and muscle regeneration in male mice

Nature Communications
Serotonin reuptake inhibitor antidepressants such as fluoxetine are widely used to treat mood disorders. The mechanisms of action include an increase in extracellular level of serotonin, neurogenesis, and growth of vessels in the brain.
Mylène Fefeu, Michael Blatzer, Anita Kneppers, David Briand, Pierre Rocheteau, Alexandre Haroche, David Hardy, Mélanie Juchet-Martin, Anne Danckaert, François Coudoré, Abdulkarim Tutakhail, Corinne Huchet, Aude Lafoux, Rémi Mounier, Olivier Mir, Raphaël Gaillard, Fabrice Chrétien   +16 more
doaj   +1 more source

Cognitive, Motor and Oculomotor Contributions to the Trail Making Test in Progressive Supranuclear Palsy

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Progressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by motor, oculomotor and cognitive impairments. Yet disentangling cognitive deficits from motor and oculomotor dysfunction remains a diagnostic and methodological challenge.
Indira Garcia‐Cordero, Mohsen Hadian, Juan Camilo Vargas‐Gonzalez, Marta Monteiro, David Gold, Abeer Khoja, Alonso Morales‐Rivero, Blas Couto, David Tang‐Wai, Susan Fox, Gabor G. Kovacs, Anthony E. Lang, Maria Carmela Tartaglia   +12 more
wiley   +1 more source

Fluoxetine inhibited RANKL-induced osteoclastic differentiation in vitro

Open Medicine
Selective serotonin reuptake inhibitor correlates with decreased bone mineral density and impedes orthodontic tooth movement. The present study aimed to examine the effects of fluoxetine on osteoclast differentiation and function.
Zhang Jing-wen, Zhao Fang-bing, Ma Bing’er, Shen Xiao-qing, Geng Yuan-ming   +4 more
doaj   +1 more source

Combining dance movement therapy and pharmacotherapy in adolescents with major depressive disorder: A randomized controlled study

Pediatric Investigation, EarlyView.
The current study was among the first clinical trials that combined dance movement therapy (DMT) and pharmacotherapy to enhance self‐esteem and alleviate anxious and depressive symptoms in adolescents with major depressive disorder. Results indicated that DMT combined with pharmacotherapy improved depression symptoms more than pharmacotherapy alone ...
Yanru Liu, Wanling Zhang, Xuejiao Sun, Xiaoxuan Fan, Na Hu, Xuanzi Zhou, Xiao Leng, Ying Li   +7 more
wiley   +1 more source

Advising on Antidepressant Use in Pregnancy: Are We All on the Same Page? [PDF]

Asia Pac Psychiatry
ABSTRACT Purpose Perinatal mood disorders are associated with adverse maternal and neonatal outcomes and affect 15%–20% of pregnant people. Guidelines recommend SSRIs when non‐pharmacological therapies are ineffective, yet antenatal depression remains undertreated.
Broughton LC, Hughes N, Zeng J, Smith A.
europepmc   +2 more sources

Medication prescription patterns in cancer rehabilitation physiatry outpatients: A multicenter retrospective study

PM&R, EarlyView.
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen, Nafis Eghrari, David Leong, Philip Chang, Jasmine Zheng, Amy Ng, Richard Wilson, Mary Vargo   +7 more
wiley   +1 more source

Polypharmacy among adolescents and adults with cerebral palsy in a clinical setting

PM&R, EarlyView.
Abstract Background Adolescents and adults with cerebral palsy often experience multimorbidity related to their condition, which primarily affects movement and posture but is also associated with pain, epilepsy, mood disorders, and other conditions. As such, these patients are often prescribed a range of medications to manage symptoms, thereby putting ...
Caitlin Cassidy, Joshua C. Wiener, Karen Pratt, Laura Brunton   +3 more
wiley   +1 more source