Frontiers in Pharmacology, 2020 Growing evidence suggests an important role of fluoxetine with serotonin 5-HT1A and 5-HT2C receptors in the modulation of emotion and nociception in brain areas such as the amygdala and periaqueductal gray (PAG).
Daniela Baptista-de-Souza +17 more
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ASN Neuro, 2021 Low dopamine levels may cause depressive symptoms. Dopamine is also involved in sexual behavior. Rotigotine is a nonergolinic dopamine agonist. Fluoxetine, an antidepressant that acts as a selective serotonin (5-HT) reuptake inhibitor, may cause moderate
Wenqian Wang +8 more
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Investigation of a role for noradrenaline in the neurochemical and behavioural effects of an established and putative target for antianxiety/antidepressant drugs: a microdialysis and behavioural study in rats and NK1 receptor knockout mice. [PDF]
, 2005 The precise neurochemical effects of antidepressants that underlie their efficacy remain unclear. Many antidepressants modulate noradrenaline transmission in vivo.
Stewart, R.J.
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Fungi and Fluoxetine: Effect of Fluoxetine on the Human Mycobiome [PDF]
, 2023 Background: The gut mycobiome and the role it plays in the gut-brain axis is an area of study in its infancy. Little is understood on how drugs might affect the mycobiome, and therefore the host.
Morgan, Rebecca, Winter, Gal
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Differential Rearing Alters Forced Swim Test Behavior, Fluoxetine Efficacy, and Post-Test Weight Gain in Male Rats. [PDF]
PLoS ONE, 2015 Environmental factors play a key role in the etiology of depression. The rodent forced swim test (FST) is commonly used as a preclinical model of depression, with increases in escape-directed behavior reflecting antidepressant effects, and increases in ...
David L Arndt +2 more
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"In vitro" study of the mode of action of antidepressants in cell culture models : comparison of the effects of "Hypericum perforatum L." extracts and classical synthetic compounds on the [beta]-adrenergic signal pathway [PDF]
, 2005 The clinical effectiveness of the plant extract of Hypericum perforatum L. in treating mild to moderate depression is well established. The extract shows a more favourable side effect profile than other antidepressant drugs, like tricyclics and selective
Wirz, Adrian
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Fluoxetine mesocosm experiment
, 2023 Fluoxetine mesocosm ...
Lara Schuijt (17295043)
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Fluoxetine brakes the menstrual cycle: Uncovering the unexpected effect
Industrial Psychiatry JournalFluoxetine is one of the most commonly used antidepressants, classified under selective serotonin reuptake inhibitors (SSRIs). It is indicated for the treatment of depression, obsessive-compulsive disorder, anxiety, and eating disorders.
Barath Ramanathan +3 more
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Neuropsychopharmacology Reports, 2019 Aims The molecular and cellular mechanisms underlying the antidepressant effects of fluoxetine in the brain are not fully understood. Emerging evidence has led to the hypothesis that chronic fluoxetine treatment induces dematuration of certain types of ...
Hideo Hagihara +2 more
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Corticosterone facilitates fluoxetine-induced neuronal plasticity in the hippocampus.
PLoS ONE, 2013 The hippocampal dentate gyrus has been implicated in a neuronal basis of antidepressant action. We have recently shown a distinct form of neuronal plasticity induced by the serotonergic antidepressant fluoxetine, that is, a reversal of maturation of the ...
Katsunori Kobayashi +5 more
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