Results 21 to 30 of about 38,009 (171)

Anxiolytic profile of fluoxetine as monitored following repeated administration in animal rat model of chronic mild stress

Saudi Pharmaceutical Journal, 2016
Background: Fluoxetine, a selective serotonin re-uptake inhibitor (SSRI), has been proposed to be more effective as an antidepressive drug as compared to other SSRIs.
Muhammad Farhan, Darakshan Jabeen Haleem
doaj   +1 more source

Chemie und Pharmazie in die Nachhaltigkeit einbetten

Angewandte Chemie, EarlyView.
Chemie und Pharmazie sind mit ihren Produkten und Prozessen grundlegend für unseren hohen Lebensstandard. Es ist wesentlich, ihre Verbindung mit der Nachhaltigkeit zu verstehen, damit sie auf nachhaltige Weise nachhaltig zur Nachhaltigkeit beitragen können.
Klaus Kümmerer
wiley   +1 more source

Fluoxetine attenuates neuroinflammation in early brain injury after subarachnoid hemorrhage: a possible role for the regulation of TLR4/MyD88/NF-κB signaling pathway

Journal of Neuroinflammation, 2018
Background Neuroinflammation is closely associated with functional outcome in subarachnoid hemorrhage (SAH) patients. Our recent study demonstrated that fluoxetine inhibited NLRP3 inflammasome activation and attenuated necrotic cell death in early brain ...
Fu-yi Liu, Jing Cai, Chun Wang, Wu Ruan, Guo-ping Guan, Hai-zhou Pan, Jian-ru Li, Cong Qian, Jing-sen Chen, Lin Wang, Gao Chen   +10 more
doaj   +1 more source

Dopamine receptor agonist rotigotine-loaded microspheres ameliorates sexual function deteriorated by fluoxetine in depression rats

ASN Neuro, 2021
Low dopamine levels may cause depressive symptoms. Dopamine is also involved in sexual behavior. Rotigotine is a nonergolinic dopamine agonist. Fluoxetine, an antidepressant that acts as a selective serotonin (5-HT) reuptake inhibitor, may cause moderate
Wenqian Wang, Ce Zhang, Yiqian Fan, Shumin Yue, Yunqi Yang, Rongxia Liu, Leiming Zhang, Tian Wang, Fenghua Fu   +8 more
doaj   +1 more source

Embedding Chemistry and Pharmacy Into Sustainability

Angewandte Chemie International Edition, EarlyView.
Chemistry and pharmacy provide products and processes that are indispensable for our high living standard. To understand their relationship with sustainability is important to allow them to contribute to sustainability in a sustainable manner. An integrated overview of green, circular, and sustainable chemistry and pharmacy is given and how they have t
Klaus Kümmerer
wiley   +1 more source

Detecting fluoxetine and norfluoxetine in wild bird tissues and feathers

Environment International, 2019
The contamination of the environment with human pharmaceuticals is widespread and demand for such products is mounting globally. Wild vertebrates may be at particular risk from any effects from pharmaceuticals, because of the evolutionary conservation of
Sophia E. Whitlock, M. Glória Pereira, Julie Lane, Darren Sleep, Richard F. Shore, Kathryn E. Arnold   +5 more
doaj   +1 more source

Chronic Fluoxetine Impairs the Effects of 5-HT1A and 5-HT2C Receptors Activation in the PAG and Amygdala on Antinociception Induced by Aversive Situation in Mice

Frontiers in Pharmacology, 2020
Growing evidence suggests an important role of fluoxetine with serotonin 5-HT1A and 5-HT2C receptors in the modulation of emotion and nociception in brain areas such as the amygdala and periaqueductal gray (PAG).
Daniela Baptista-de-Souza, Daniela Baptista-de-Souza, Daniela Baptista-de-Souza, Lígia Renata Rodrigues Tavares, Lígia Renata Rodrigues Tavares, Elke Mayumi Furuya-da-Cunha, Elke Mayumi Furuya-da-Cunha, Paulo Eduardo Carneiro de Oliveira, Paulo Eduardo Carneiro de Oliveira, Lucas Canto-de-Souza, Lucas Canto-de-Souza, Ricardo Luiz Nunes-de-Souza, Ricardo Luiz Nunes-de-Souza, Ricardo Luiz Nunes-de-Souza, Azair Canto-de-Souza, Azair Canto-de-Souza, Azair Canto-de-Souza, Azair Canto-de-Souza   +17 more
doaj   +1 more source

Prescribing competence: The pros and cons of different methods for assessment

British Journal of Clinical Pharmacology, EarlyView.
Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman, Erik M. Donker, Jelle Tichelaar, on behalf of the CP4T programme   +3 more
wiley   +1 more source

Deep Brain Stimulation Reduces Conflict‐Related Theta and Error‐Related Negativity in Patients With Obsessive–Compulsive Disorder

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Obsessive–compulsive disorder (OCD) is a psychiatric disorder with alterations of cortico‐striato‐thalamo‐cortical loops and impaired performance monitoring. Electrophysiological markers such as conflict‐related medial frontal theta (MFT) and error‐related negativity (ERN) may be altered by clinically effective deep brain ...
Elena Sildatke, Theo O. J. Gruendler, Markus Ullsperger, Till A. Dembek, Juan Carlos Baldermann, Sina Kohl, Veerle Visser‐Vandewalle, Daniel Huys, Jens Kuhn, Thomas Schüller   +9 more
wiley   +1 more source

Transcriptomic evidence for immaturity induced by antidepressant fluoxetine in the hippocampus and prefrontal cortex

Neuropsychopharmacology Reports, 2019
Aims The molecular and cellular mechanisms underlying the antidepressant effects of fluoxetine in the brain are not fully understood. Emerging evidence has led to the hypothesis that chronic fluoxetine treatment induces dematuration of certain types of ...
Hideo Hagihara, Koji Ohira, Tsuyoshi Miyakawa   +2 more
doaj   +1 more source