Results 11 to 20 of about 52,111 (191)

Fluoxetine disrupts cholesterol metabolism in endothelial cells via SREBP2 activation [PDF]

open access: yesTranslational Psychiatry
Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) commonly prescribed for the treatment of depressive disorders. Recent clinical reports and studies in animal models have suggested that fluoxetine increases the risk of cardiovascular diseases,
Fabiana Oliveira   +28 more
doaj   +2 more sources

Possible Cognitive Dysfunction Associated With High-Dose Fluoxetine in a Patient on Lithium [PDF]

open access: yesCase Reports in Psychiatry
Antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine, are widely prescribed medications. Fluoxetine is considered a first-line pharmacological treatment for common psychiatric conditions such as anxiety ...
Adina Tanen, Amy Rajan, Alan Kahn
doaj   +2 more sources

Testing of analgesic effect of fluoxetine [PDF]

open access: yesBiomolecules & Biomedicine, 2004
Fluoxetine is used in treatment of depression caused by a variety of different factors and from year to year new indications are being added, especially in conditions followed with strong bouts of pain.
Amra Begović   +2 more
doaj   +2 more sources

Fluoxetine Potentiates Phagocytosis and Autophagy in Microglia

open access: yesFrontiers in Pharmacology, 2021
Fluoxetine is a classic antidepressant drug, and its immunomodulatory effects have recently been reported in many disease models. In addition, it has strong antineuroinflammatory effects in stroke and neurodegenerative animal models.
Sung Hee Park   +5 more
doaj   +1 more source

Assessing the Mechanism of Fluoxetine-Mediated CYP2D6 Inhibition

open access: yesPharmaceutics, 2021
Fluoxetine is still one of the most widely used antidepressants in the world. The drug is extensively metabolized by several cytochrome P450 (CYP450) enzymes and subjected to a myriad of CYP450-mediated drug interactions.
Malavika Deodhar   +4 more
doaj   +1 more source

Fluoxetine exerts age-dependent effects on behavior and amygdala neuroplasticity in the rat. [PDF]

open access: yesPLoS ONE, 2011
The selective serotonin reuptake inhibitor (SSRI) Prozac® (fluoxetine) is the only registered antidepressant to treat depression in children and adolescents.
Judith R Homberg   +8 more
doaj   +1 more source

Analysis of Adherence to Fluoxetine Treatment through its Plasma Concentration

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2023
Depression plays an important role in non-adherence to medical recommendations. Fluoxetine is a first line of depression treatment. This study aimed to evaluate adherence to drug therapy in fluoxetine users by different methods. A cross-section study was
Juliana Raquel Raasch   +8 more
doaj   +1 more source

Antidepressants Fluoxetine Mediates Endoplasmic Reticulum Stress and Autophagy of Non–Small Cell Lung Cancer Cells Through the ATF4-AKT-mTOR Signaling Pathway

open access: yesFrontiers in Pharmacology, 2022
Fluoxetine, one of the latest clinical antidepressants, is reported to have the anti-proliferative effect on cancer cells via immune-related pathways. However, the mechanism is still not known.
Shali Shao   +3 more
doaj   +1 more source

Fluoxetine improves bone microarchitecture and mechanical properties in rodents undergoing chronic mild stress – an animal model of depression

open access: yesTranslational Psychiatry, 2022
Depression is one of the most prevalent mental disorders associated with reductions in bone mineral density and increased fracture risk. Fluoxetine is a highly prescribed selective serotonin reuptake inhibitor (SSRI) in the treatment of depression and is
Raymond W. Lam   +6 more
doaj   +1 more source

Factors associated with fluoxetine and norfluoxetine plasma concentrations and clinical response in Mexican patients with mental disorders

open access: yesPharmacology Research & Perspectives, 2021
Over the last few years, fluoxetine has been one of the most prescribed medications for the treatment of diverse psychiatric conditions in Mexico.
Julia Sagahón‐Azúa   +5 more
doaj   +1 more source

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