Viruses, 2019 This study reports the antiviral activity of the drug fluoxetine against some enteroviruses (EV). We had previously established a model of persistent coxsackievirus B4 (CVB4) infection in pancreatic cell cultures and demonstrated that fluoxetine could ...
Enagnon Kazali Alidjinou +5 more
doaj +1 more source
Quantitative cross-species extrapolation between humans and fish: The case of the anti-depressant fluoxetine [PDF]
, 2014 This article has been made available through the Brunel Open Access Publishing Fund.Fish are an important model for the pharmacological and toxicological characterization of human pharmaceuticals in drug discovery, drug safety assessment and ...
ABA Boxall +80 more
core +3 more sources
Fluoxetine Prevents the Development of Depressive-like Behavior in a Mouse Model of Cancer Related Fatigue [PDF]
, 2015 Cancer patients frequently suffer from fatigue, a complex syndrome associated with tiredness and depressed mood. Cancer-related fatigue (CRF) can be present at the time of diagnosis, escalates during treatment, and can persist for years after treatment ...
Bicer, Sabahattin +7 more
core +2 more sources
Frontiers in Behavioral Neuroscience, 2021 Impaired behavioral activation and effort-related motivational dysfunctions like fatigue and anergia are debilitating treatment-resistant symptoms of depression. Depressed people show a bias towards the selection of low effort activities. To determine if
Carla Carratalá-Ros +5 more
doaj +1 more source
Impact of fluoxetine on testosterone levels and spermatogenic cell production of male albino mice [PDF]
Caspian Journal of Environmental Sciences, 2023 Fluoxetine is a widely used antidepressant that acts as a selective serotonin reuptake inhibitor. This study investigated the effects of fluoxetine hydrochloride on the hypothalamic-pituitary-testicular axis and spermatogenesis in male albino mice. Fifty
Mardan N. Julanov +8 more
doaj +1 more source
Fluoxetine reduces murine graft-versus-host disease by induction of T cell immunosuppression [PDF]
, 2013 Serotonin reuptake inhibitors (SRIs) are widely used drugs in the treatment of depression and anxiety disorders. Although SRIs are generally regarded as safe drugs with relatively few side effects, literature suggests that high concentrations of SRIs may
Billiau, An D +6 more
core +3 more sources
Terminal differentiation of adult hippocampal progenitor cells is a step functionally dissociable from proliferation and is controlled by Tis21, Id3 and NeuroD2 [PDF]
, 2017 Cell proliferation and differentiation are interdependent processes. Here, we have asked to what extent the two processes of neural progenitor cell amplification and differentiation are functionally separated.
Daniele Saraulli +9 more
core +2 more sources
Oxytocin exerts harmful cardiac repolarization prolonging effects in drug-induced LQTS
International Journal of Cardiology: Heart & Vasculature, 2022 Background: Oxytocin is used therapeutically in psychiatric patients. Many of these also receive anti-depressant or anti-psychotic drugs causing acquired long-QT-syndrome (LQTS) by blocking HERG/IKr.
Paul Kreifels +12 more
doaj +1 more source
Direct health care costs of treating seasonal affective disorder: a comparison of light therapy and fluoxetine. [PDF]
, 2012 Objective. To compare the direct mental health care costs between individuals with Seasonal Affective Disorder randomized to either fluoxetine or light therapy. Methods. Data from the CANSAD study was used.
Browne, Gina +8 more
core +2 more sources
Open Channel Block of Kv3.1 Currents by Fluoxetine
Journal of Pharmacological Sciences, 2008 The action of fluoxetine, a serotonin reuptake inhibitor, on the cloned neuronal rat Kv3.1 channels stably expressed in Chinese hamster ovary cells was investigated using the whole-cell patch-clamp technique.
Min Ji Sung +3 more
doaj +1 more source