The lung function profile of once-daily tiotropium and olodaterol via Respimat® is superior to that of twice-daily salmeterol and fluticasone propionate via Accuhaler® (ENERGITO® study) [PDF]
, 2016 Background: Tiotropium + olodaterol has demonstrated improvements beyond lung function benefits in a large Phase III clinical program as a once-daily maintenance treatment for COPD and may be a potential option for the initiation of maintenance treatment
Beeh, Kai-Michael +8 more
core +2 more sources
Inhaled corticosteroids versus long-acting beta -agonists for chronic obstructive pulmonary disease (Review). [PDF]
, 2011 Long-acting beta(2)-agonists and inhaled corticosteroids can be used as maintenance therapy by patients with moderate to severe chronic obstructive pulmonary disease. These interventions are often taken together in a combination inhaler.
Agarwal +105 more
core +2 more sources
Combination fluticasone and salmeterol versus fixed dose combination budesonide and formoterol for chronic asthma in adults and children [PDF]
, 2008 BackgroundCombination therapies are frequently recommended as maintenance therapy for people with asthma, whose disease is not adequately controlled with inhaled steroids.
Aalbers +64 more
core +1 more source
Effects of Budesonide and Fluticasone Propionate in Pediatric Asthma Patients
Pediatrics and Neonatology, 2010 Cytokines and chemokines play important roles in asthma. However, little information exists on the effects of inhaled corticosteroids on cytokine and chemokine plasma levels in childhood asthma.
Lin-Yu Kuo +5 more
doaj +1 more source
Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease. [PDF]
, 2014 BACKGROUND: Inhaled corticosteroids (ICS) are anti-inflammatory drugs that have proven benefits for people with worsening symptoms of chronic obstructive pulmonary disease (COPD) and repeated exacerbations.
Agarwal +163 more
core +1 more source
Педиатрическая фармакология, 2012 Aim. To compare in vitro the aerodynamic particle size distributions of original and generic inhalers, which contain both fluticasone (FP) and salmeterol (SM).Material and methods.
L. A. Trukhacheva +2 more
doaj +1 more source
Combination inhaled steroid and long-acting beta2-agonist versus tiotropium for chronic obstructive pulmonary disease [PDF]
, 2010 Background Combination therapy (inhaled corticosteroids and long-acting beta(2)-agonists) and tiotropium are both used in the treatment of chronic obstructive pulmonary disease (COPD).
Appleton +20 more
core +1 more source
Safety and efficacy of fluticasone propionate in the topical treatment of skin diseases [PDF]
, 2004 Fluticasone propionate - the first carbothioate corticosteroid - has been classified as a potent anti-inflammatory drug for dermatological use. It is available as 0.05% cream and 0.005% ointment formulations for the acute and maintenance treatment of ...
Atsuta J +33 more
core +1 more source
Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an inhaled corticosteroid for chronic asthma: serious adverse events [PDF]
, 2010 Background An increase in serious adverse events with both regular formoterol and regular salmeterol in chronic asthma has been demonstrated in comparison with placebo in previous Cochrane reviews.
Aalbers +27 more
core +2 more sources
Fluticasone/salmeterol reduces remodelling and neutrophilic inflammation in severe equine asthma
Scientific Reports, 2017 Asthmatic airways are inflamed and undergo remodelling. Inhaled corticosteroids and long-acting β2-agonist combinations are more effective than inhaled corticosteroid monotherapy in controlling disease exacerbations, but their effect on airway ...
Michela Bullone +4 more
doaj +1 more source