Results 111 to 120 of about 1,999,262 (350)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

OPERATION ANTARES : Flux de matière dans l' Océan Austral

, 1989
Le Programme Flux Océaniques (PFO) a l'ambition de déterminer, à l'échelle de l'océan global, le flux de matière, essentiellement biogénique, qui disparaît de la couche superficielle, se dépose sur les fonds océaniques et, dans son devenir ultime, quitte
Programme flux océaniques, -
core   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Rotor integrity design for a high-speed modular air-cored axial-flux permanent-magnet generator [PDF]

, 2011
The rotor integrity design for a high-speed modular air-cored axial-flux permanent-magnet (AFPM) generator is presented. The main focus is on the mechanical parametric optimization of the rotor, which becomes a more dominating design issue over ...
Luk, Patrick Chi-Kwong, El-Hasan, T. S., P. C. K. Luk, Fei, Wei-Zhong, W. Fei, T. S. El-Hasan   +5 more
core   +1 more source

Antiproton Flux, Antiproton-to-Proton Flux Ratio, and Properties of Elementary Particle Fluxes in Primary Cosmic Rays Measured with the Alpha Magnetic Spectrometer on the International Space Station.

Physical Review Letters, 2016
A precision measurement by AMS of the antiproton flux and the antiproton-to-proton flux ratio in primary cosmic rays in the absolute rigidity range from 1 to 450 GV is presented based on 3.49×10^{5} antiproton events and 2.42×10^{9} proton events.
M. Aguilar, L. Ali Cavasonza, B. Alpat, G. Ambrosi, L. Arruda, N. Attig, S. Aupetit, P. Azzarello, A. Bachlechner, F. Barão, A. Barrau, L. Barrin, A. Bartoloni, L. Basara, S. Başeğmez-du Pree, M. Battarbee, R. Battiston, J. Bazo, U. Becker, M. Behlmann, B. Beischer, J. Berdugo, B. Bertucci, V. Bindi, G. Boella, W. de Boer, K. Bollweg, V. Bonnivard, B. Borgia, M. Boschini, M. Bourquin, E. Bueno, J. Burger, F. Cadoux, X. Cai, M. Capell, S. Caroff, J. Casaus, G. Castellini, I. Cernuda, F. Cervelli, M. Chae, Y. H. Chang, A. Chen, G. Chen, H. Chen, L. Cheng, H. Chou, E. Choumilov, V. Choutko, C. Chung, C. Clark, R. Clavero, Nicolas Produit, C. Consolandi, A. Contin, C. Corti, B. Coste, W. Creus, M. Crispoltoni, Z. Cui, Y. Dai, C. Delgado, S. Della Torre, M. Demirköz, L. Derome, S. Di Falco, F. Dimiccoli, C. Díaz, P. von Doetinchem, F. Dong, F. Donnini, M. Duranti, D. D’Urso, A. Egorov, A. Eline, T. Eronen, J. Feng, E. Fiandrini, E. Finch, P. Fisher, V. Formato, Y. Galaktionov, G. Gallucci, B. Garcia, R. García-López, C. Gargiulo, H. Gast, I. Gebauer, M. Gervasi, A. Ghelfi, F. Giovacchini, P. Goglov, D. Gómez-Coral, J. Gong, C. Goy, V. Grabski, D. Grandi, M. Graziani, I. Guerri, K. Guo, M. Habiby, S. Haino, K. Han, Z. H. He, M. Heil, J. Hoffman, T. Hsieh, H. Huang, Z. Huang, C. Huh, M. Incagli, M. Ionica, W. Jang, H. Jinchi, S. Kang, K. Kanishev, G. Kim, K. Kim, T. Kirn, C. Konak, O. Kounina, A. Kounine, V. Koutsenko, Matthew Scott Krafczyk, G. La Vacca, E. Laudi, G. Laurenti, I. Lazzizzera, A. Lebedev, H. T. Lee, S. Lee, C. Leluc, H. S. Li, J. Li, J. Li, Q. Li, T. X. Li, W. Li, Z. Li, Z. Li, S. Lim, C. H. Lin, P. Lipari, T. Lippert, D. Liu, Hu Liu, S. Lu, Y. Lu, K. Luebelsmeyer, F. Luo, J. Luo, S. Lv, R. Majka, C. Mañá, J. Marin, T. Martin, G. Martinez, N. Masi, D. Maurin, A. Menchaca-Rocha, Q. Meng, D. Mo, L. Morescalchi, P. Mott, T. Nelson, J. Ni, N. Nikonov, F. Nozzoli, P. Nunes, A. Oliva, M. Orcinha, Federico Palmonari, C. Palomares, M. Paniccia, M. Pauluzzi, S. Pensotti, R. Pereira, N. Picot-Clemente, F. Pilo, C. Pizzolotto, V. Plyaskin, M. Pohl, V. Poireau, A. Putze, L. Quadrani, X. Qi, X. Qin, Z. Qu, T. Räihä, P. Rancoita, D. Rapin, J. Ricol, I. Rodríguez, S. Rosier-Lees, A. Rozhkov, D. Rozza, R. Sagdeev, J. Sandweiss, P. Saouter, S. Schael, S. M. Schmidt, A. Schulz von Dratzig, G. Schwering, E. Seo, B. Shan, J. Shi, T. Siedenburg, D. Son, J. Song, W. Sun, M. Tacconi, X. Tang, Z. Tang, L. Tao, D. Tescaro, S. Ting, S. Ting, N. Tomassetti, J. Torsti, C. Türkoğlu, T. Urban, V. Vagelli, E. Valente, C. Vannini, E. Valtonen, M. Vazquez Acosta, M. Vecchi, M. Velasco, J. Vialle, V. Vitale, S. Vitillo, L. Wang, N. Wang, Q. Wang, X. Wang, X. Wang, Z. Wang, C. C. Wei, Z. Weng, K. Whitman, J. Wienkenhöver, M. Willenbrock, H. Wu, X. Wu, X. Xia, R. Xiong, W. Xu, Qi Yan, J. Yang, M. Yang, Y. Yang, H. Yi, Y. Yu, Z. Yu, S. Zeissler, C. Zhang, J. Zhang, J. Zhang, S. Zhang, S. Zhang, Z. Zhang, Z. Zheng, Z. Q. Zhu, H. Zhuang, V. Zhukov, A. Zichichi, N. Zimmermann, P. Zuccon   +268 more
semanticscholar   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Investigation of torque characteristics in a novel permanent magnet flux switching machine with an outer-rotor configuration [PDF]

, 2014
This paper comprehensively investigates the torque characteristics of a novel permanent magnet flux switching machine with outer-rotor configuration.
Miao, Dong-Min, Shen, Jian-Xin, Luk, Patrick Chi-Kwong, Fei, Wei-Zhong   +3 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source