Results 91 to 100 of about 2,311,044 (291)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Non-commutative M-branes from Open Pure Spinor Supermembrane

, 2018
Open supermembrane with a constant three-form flux in the pure spinor formalism is examined. The BRST symmetry of the open supermembrane action leads to non-commutative (NC) M-branes. In addition to the NC M5-brane with a self-dual two-form flux, we find
Hanazawa, Sota, Sakaguchi, Makoto
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Cryogenic flux-concentrator [PDF]

, 1969
Flux concentrator has high primary to secondary coupling efficiency enabling it to produce high magnetic fields.
Bailey, B. M., Brechna, H., Hill, D. A.
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Movement of cholesterol in vitro in rat blood and quantitation of the exchange of free cholesterol between plasma and erythrocytes

Journal of Lipid Research, 1972
After administration of [4-14C]cholesterol to rats, blood was obtained and incubated for 6 hr or less. Incubation resulted in a net loss of erythrocyte cholesterol and, simultaneously, in an increase of esterified cholesterol in plasma and a-lipoproteins.
F. d'Hollander, F. Chevallier
doaj   +1 more source

Influence of vortex-vortex interaction on critical currents across low-angle grain boundaries in YBa2Cu3O7-delta thin films

, 2000
Low-angle grain boundaries with misorientation angles theta < 5 degrees in optimally doped thin films of YBCO are investigated by magnetooptical imaging.
A. A. Polyanskii, A. Gurevich, A. Gurevich, A. Gurevich, A. P. Sutton, A. Pruymboom, B. H. Moeckly, Ch. Jooss, Ch. Jooss, D. Dimos, D. N. Basov, E. H. Brandt, H. Hilgenkamp, H. Hilgenkamp, H. Kronmüller, J. A. Alarco, J. Albrecht, J. B. Hirth, J. Halbritter, J. L. Tallon, J. M. Huijbregtse, J. Mannhart, K. E. Gray, L. A. Dorosinskii, M. F. Chisholm, N. F. Heinig, P. G. de Gennes, R. Gross, R. Gross, R. Wijngaarden, S. Leonhardt, Th. Schuster, Z. G. Ivanov   +32 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Flux cost functions and the choice of metabolic fluxes

, 2018
Metabolic fluxes in cells are governed by physical, biochemical, physiological, and economic principles. Cells may show "economical" behaviour, trading metabolic performance against the costly side-effects of high enzyme or metabolite concentrations ...
Liebermeister, Wolfram
core  

MHD Modeling for Formation Process of Coronal Mass Ejections: Interaction between Ejecting Flux Rope and Ambient Field

, 2010
We performed magnetohydrodynamic simulation of a formation process of coronal mass ejections (CMEs), focusing on interaction (reconnection) between an ejecting flux rope and its ambient field.
Antiochos, Aoki, Chen, Choe, Daikou Shiota, Galsgaard, Inoue, Kanya Kusano, Kazunari Shibata, Kim, Kusano, Lynch, Sakajiri, Shimizu, Shiota, Sterling, Takahiro Miyoshi, Török, Yashiro, Yurchyshyn, Yurchyshyn   +20 more
core   +1 more source