Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Static flux bias of a flux qubit using persistent current trapping [PDF]
Qubits based on the magnetic flux degree of freedom require a flux bias, whose stability and precision strongly affect the qubit performance, up to a point of forbidding the qubit operation.
Chiarello F +7 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Triggering an eruptive flare by emerging flux in a solar active-region complex
A flare and fast coronal mass ejection originated between solar active regions NOAA 11514 and 11515 on July 1, 2012 in response to flux emergence in front of the leading sunspot of the trailing region 11515.
A.A. Ballegooijen van +60 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Stirred cell ultrafiltration of lignin from black liquor generated from South African kraft mills
Ultrafiltration of lignin from black liquor was carried out in a stirred batch cell using polyethersulfone membranes. Parameters such as operating pressure, feed concentration, stirring rate and membrane cut-off size were varied and their effects on ...
Paul Kekana +2 more
doaj +1 more source
A magnetic flux pump is described for increasing the intensity of a magnetic field by transferring flux from one location to the magnetic field. The device includes a pair of communicating cavities formed in a block of superconducting material, and a ...
Elleman, D. D. +2 more
core +1 more source
Signatures of magnetic reconnection at boundaries of interplanetary small-scale magnetic flux ropes
The interaction between interplanetary small-scale magnetic flux ropes and the magnetic field in the ambient solar wind is an important topic to understand- ing the evolution of magnetic structures in the heliosphere.
Cartwright +16 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Modeling of milk ultrafiltration permeate flux under various operating conditions and physicochemical properties using Nero–Fuzzy method [PDF]
In this study, an adaptive neuro-fuzzy inference system (ANFIS) used for the prediction of permeate flux as a function of the physico-chemical and operating parameters during ultrafiltration of milk.
Mahnaz Shahidi Noghabi +2 more
doaj +1 more source

