Results 91 to 100 of about 1,555,219 (293)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Frontiers in Microbiology, 2013 Synthetic biology enables metabolic engineering of industrial microbes to synthesize value-added molecules. In this, a major challenge is the efficient redirection of carbon to the desired metabolic pathways.
Ashish eMisra +6 more
doaj +1 more source
IET Electric Power Applications, 2022 In this paper, a novel variable‐leakage‐flux interior permanent magnet (VLF‐IPM) motor is proposed, which is a kind of mechanical flux‐adjusting PM motor.
Jianwei Liang +4 more
doaj +1 more source
Flux balance analysis: A geometric perspective [PDF]
Journal of Theoretical Biology, 2009 Advances in the field of bioinformatics have led to reconstruction of genome-scale networks for a number of key organisms. The application of physicochemical constraints to these stoichiometric networks allows researchers, through methods such as flux balance analysis, to highlight key sets of reactions necessary to achieve particular objectives.
Smallbone, Kieran, Simeonidis, Evangelos
openaire +3 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Predictive Sulfur Metabolism - a field in flux
Frontiers in Plant Science, 2014 The key role of sulfur metabolites in response to biotic and abiotic stress in plants, as well as their importance in diet and health has led to a significant interest and effort in trying to understand and manipulate the production of relevant compounds.
Alexander eCalderwood +2 more
doaj +1 more source
, 2019 For string theory on AdS$_3$ with pure NS-NS flux a complete set of DDF operators is constructed, from which one can read off the symmetry algebra of the spacetime CFT.
Eberhardt, Lorenz +1 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
p13CMFA: Parsimonious 13C metabolic flux analysis.
PLoS Computational Biology, 2019 Deciphering the mechanisms of regulation of metabolic networks subjected to perturbations, including disease states and drug-induced stress, relies on tracing metabolic fluxes.
Carles Foguet +7 more
doaj +1 more source
Synthetic Biology of Cyanobacteria: Unique Challenges and Opportunities
Frontiers in Microbiology, 2013 Photosynthetic organisms, and especially cyanobacteria, hold great promise as sources of renewably-produced fuels, bulk and specialty chemicals, and nutritional products.
Bertram M Berla +5 more
doaj +1 more source