Results 111 to 120 of about 1,555,219 (293)

Using the Maximum X-ray Flux Ratio and X-ray Background to Predict Solar Flare Class

, 2015
We present the discovery of a relationship between the maximum ratio of the flare flux (namely, 0.5-4 Ang to the 1-8 Ang flux) and non-flare background (namely, the 1-8 Ang background flux), which clearly separates flares into classes by peak flux level.
Balasubramaniam, K., Winter, Lisa M.
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Removal of endocrine disrupting chemicals using low pressure reverse osmosis membrane [PDF]

, 2009
Endocrine disrupting chemicals (EDCs) are one of the major focuses of contaminants in current environmental issues, as they can cause adverse health effects on animals and human, particularly to endocrine function.
Abd. Razak, Azri Rasyidi
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Onsager Loop-Transition and First Order Flux-Line Lattice Melting in High-$T_c$ Superconductors

, 1997
Monte-Carlo simulations in conjunction with finite-size scaling analysis are used to investigate the $(H,T)$-phase diagram in uniaxial anisotropic high- $T_c$ superconductors, both in zero magnetic field and in intermediate magnetic fields for various ...
A. Houghton, A. Junod, A. K. Nguyen, A. K. Nguyen, A. P. Young, A. Schilling, A. Schilling, A. Sudbø, A. Sudbø, A. Sudbø, A. Sudbø, B. Chattopadhyay, B. Horovitz, C. Dasgupta, D. R. Nelson, D. R. Nelson, D. R. Nelson, D. R. Nelson, D. R. Nelson, D. R. Nelson, E. Frey, E. H. Brandt, E. Zeldov, G. Blatter, G. Carneiro, G. Williams, H. Pastoriza, H. Safar, J. Friedel, J. Friedel, J. M. Kosterlitz, J. Villain, L. Onsager, M. Franz, M. V. Feigel’man, N. Morozov, R. A. Doyle, R. Cavalcanti, R. Cavalcanti, R. E. Hetzel, R. P. Feynman, S. E. Korshunov, S. Hattel, S. Hattel, T. Chen, T. Chen, T. Chen, T. Nishikazi, U. Welp, W. Janke, Ying-Hong Li, Ying-Hong Li, Z. Tešanović   +52 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Origin of the high energy neutrino flux at IceCube

, 2017
We discuss the spectrum of the different components in the astrophysical neutrino flux reaching the Earth and the possible contribution of each component to the high-energy IceCube data. We show that the diffuse flux from cosmic ray interactions with gas
Carceller, J. M., Illana, J. I., Masip, M., Meloni, D.   +3 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Enhanced flux potential analysis links changes in enzyme expression to metabolic flux

Molecular Systems Biology
Algorithms that constrain metabolic network models with enzyme levels to predict metabolic activity assume that changes in enzyme levels are indicative of flux variations.
Xuhang Li, Albertha J M Walhout, L Safak Yilmaz   +2 more
doaj   +1 more source