Results 251 to 260 of about 1,555,219 (293)
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Journal of Biotechnology, 1999
Flux analysis has been dealing with the calculation of internal fluxes using external measurements. Although it provides useful insight, the analysis has little predictive power. Building on the existing analysis, inverse flux analysis was developed, which aims to predict the flux distribution based on intrinsic regulatory constraints. It is known that
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Flux analysis has been dealing with the calculation of internal fluxes using external measurements. Although it provides useful insight, the analysis has little predictive power. Building on the existing analysis, inverse flux analysis was developed, which aims to predict the flux distribution based on intrinsic regulatory constraints. It is known that
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Genetically constrained metabolic flux analysis
Metabolic Engineering, 2005Significant progress has been made in using existing metabolic databases to estimate metabolic fluxes. Traditional metabolic flux analysis generally starts with a predetermined metabolic network. This approach has been employed successfully to analyze the behaviors of recombinant strains by manually adding or removing the corresponding pathway(s) in ...
Steven J, Cox +3 more
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Metabolic Flux Analysis and Visualization
Journal of Proteome Research, 2011One of the ultimate goals of systems biology research is to obtain a comprehensive understanding of the control mechanisms of complex cellular metabolisms. Metabolic Flux Analysis (MFA) is a important method for the quantitative estimation of intracellular metabolic flows through metabolic pathways and the elucidation of cellular physiology.
Yoshihiro, Toya +3 more
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Thermodynamic Approaches in Flux Analysis
2020Networks of reactions inside the cell are constrained by the laws of mass and energy balance. Constrained-based modelling (CBM) is the most used method to describe the mass balance of metabolic network. The main key concepts in CBM are stoichiometric analysis such as elementary flux mode analysis or flux balance analysis.
Peres, Sabine, Fromion, Vincent
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Flux‐coupled genes and their use in metabolic flux analysis
Biotechnology Journal, 2013AbstractAs large volumes of omics data have become available, systems biology is playing increasingly important roles in elucidating new biological phenomena, especially through genome‐scale metabolic network modeling and simulation. Much effort has been exerted on integrating omics data with metabolic flux simulation, but further development is ...
Kim, H.U. Kim, Hyun Uk +2 more
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1997
Abstract Flux analysis is a method of organizing data which shows the quantitative relationships among all the metabolic events going on in a fermentation. It is a simple description of what is actually happening in the fermentation and does not, in itself, consider the theory of how fermentations are limited or controlled.
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Abstract Flux analysis is a method of organizing data which shows the quantitative relationships among all the metabolic events going on in a fermentation. It is a simple description of what is actually happening in the fermentation and does not, in itself, consider the theory of how fermentations are limited or controlled.
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Metabolic flux analysis in biotechnology processes
Biotechnology Letters, 2008Metabolic flux analysis (MFA) has become a fundamental tool of metabolic engineering to elucidate the metabolic state of the cell and has been applied to various biotechnological processes. In recent years, considerable technical advances have been made.
Shintaro, Iwatani +2 more
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Urban biogeochemical flux analysis
2015Biogeochemical fluxes-the movement of materials among components of ecosystems and between different ecosystems-are fundamental ecological processes. Biogeochemical fluxes usually are defined for elements, rather than compounds. Biogeochemical cycles involve changes in form due to chemical, physical and organism-mediated processes, physical or ...
Nancy B. Grimm +3 more
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2014
Metabolic Flux Analysis: Methods and Protocols opens up the field of metabolic flux analysis to those who want to start a new flux analysis project but are overwhelmed by the complexity of the approach. Metabolic flux analysis emerged from the current limitation for the prediction of metabolic fluxes from a measured inventory of the cell.
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Metabolic Flux Analysis: Methods and Protocols opens up the field of metabolic flux analysis to those who want to start a new flux analysis project but are overwhelmed by the complexity of the approach. Metabolic flux analysis emerged from the current limitation for the prediction of metabolic fluxes from a measured inventory of the cell.
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Mass spectrometry for metabolic flux analysis
Biotechnology & Bioengineering, 1999Mass spectrometry in combination with tracer experiments based on 13C substrates can serve as a powerful tool for the modeling and analysis of intracellular fluxes and the investigation of biochemical networks. The theoretical background for the application of mass spectrometry to metabolic flux analysis is discussed.
, Wittmann, , Heinzle
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