Results 81 to 90 of about 1,555,219 (293)

Multiscaling of galactic cosmic ray flux

, 2003
Multiscaling analysis of differential flux dissipation rate of galactic cosmic rays (Carbon nuclei) is performed in the energy ranges: 56.3-73.4 Mev/nucleon and 183.1-198.7 MeV/nucleon, using the data collected by ACE/CRIS spacecraft instrument for 2000 ...
A. Bershadskii, A. Bershadskii, A. Bialas, A. Bialas, A. C. Monin, E. Marsch, J. W. Bieber, K. Kudela, L. A. Fisk, M. L. Goldstein, M. V. Alania, O. Stawicki, R. Benzi, R. Schlickeiser, T. S. Horbury, T. S. Horbury, W. H. Matthaeus   +16 more
core   +1 more source

Quantifying Dynamic Regulation in Metabolic Pathways with Nonparametric Flux Inference [PDF]

, 2019
One of the central tasks in systems biology is to understand how cells regulate their metabolism. Hierarchical regulation analysis is a powerful tool to study this regulation at the metabolic, gene-expression, and signaling levels.
He, Fei, Stumpf, Michael P H
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

13C-based metabolic flux analysis

Nature Protocols, 2009
Stable isotope, and in particular (13)C-based flux analysis, is the exclusive approach to experimentally quantify the integrated responses of metabolic networks. Here we describe a protocol that is based on growing microbes on (13)C-labeled glucose and subsequent gas chromatography mass spectrometric detection of (13)C-patterns in protein-bound amino ...
Zamboni, Nicola, Fendt, Sarah-Maria, Rühl, Martin, Sauer, Uwe   +3 more
openaire   +4 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Lyman alpha dominance of the Classical T Tauri FUV Radiation Field

, 2012
Far-ultraviolet (FUV) radiation plays an important role in determining chemical abundances in protoplanetary disks. HI Lyman alpha is suspected to be the dominant component of the FUV emission from Classical T Tauri Stars (CTTSs), but is difficult to ...
Aikawa, Ardila, Ayres, Bergin, Bergin, Bethell, Fogel, France, France, France, Gorti, Green, Herczeg, Herczeg, Herczeg, Herczeg, Ingleby, Markwardt, Nomura, Saucedo, Schindhelm, Valenti, Walter, Wood, Wood, Yang, Yang   +26 more
core   +1 more source

Software applications for flux balance analysis [PDF]

Briefings in Bioinformatics, 2012
Flux balance analysis (FBA) is a widely used computational method for characterizing and engineering intrinsic cellular metabolism. The increasing number of its successful applications and growing popularity are possibly attributable to the availability of specific software tools for FBA.
Lakshmanan, M., Koh, G., Chung, B.K.S., Lee, D.-Y.   +3 more
openaire   +2 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Topological analysis of carbon flux during multi-stress adaptation in Halomonas sp. AAD12

Electronic Journal of Biotechnology, 2015
Background: Osmolytes with their effective stabilizing properties are accumulated as protectants not only against salinity but also against denaturing harsh environmental stresses such as freezing, drying, high temperatures, oxygen radicals and radiation.
Hilal Mangaoglu Yoruk, Nihat Alpagu Sayar   +1 more
doaj   +1 more source

Fiber-Flux Diffusion Density for White Matter Tracts Analysis: Application to Mild Anomalies Localization in Contact Sports Players

, 2017
We present the concept of fiber-flux density for locally quantifying white matter (WM) fiber bundles. By combining scalar diffusivity measures (e.g., fractional anisotropy) with fiber-flux measurements, we define new local descriptors called Fiber-Flux ...
C Stamile, E Garyfallidis, E Garyfallidis, FC Yeh, J Mårtensson, J Sethian, JB Colby, JD Yeatman, L Heimer, L O’Donnell, L Younes, LJ O’Donnell, LJ O’Donnell, M Khatami, MB Hulkower, ME Shenton, MK Chung, N Charon, P Basser, PA Yushkevich, S Durrleman, S Mori, SM Smith, TB Sebastian, Y Benjamini   +24 more
core   +1 more source