Results 121 to 130 of about 4,706,491 (312)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
BMC Systems Biology, 2011 BackgroundElementary flux modes (EFM) are unique and non-decomposable sets of metabolic reactions able to operate coherently in steady-state. A metabolic network has in general a very high number of EFM reflecting the typical functional redundancy of ...
A. Ferreira +7 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Scattering of p-Modes by a Thin Magnetic Flux Tube [PDF]
, 2020 There is strong observational evidence for solar p-modes being scattered by sunspots. Understanding and comparing phase shifts or travel time delays of scattered waves can present an opportunity to deduce the subsurface structure of sunspots from the ...
Mykola Gordovskyy, Rekha Jain
core
Persistent current in 2D topological superconductors
Scientific Reports, 2017 A junction between two boundaries of a topological superconductor (TSC), mediated by localized edge modes of Majorana fermions, is investigated. The tunneling of fermions across the junction depends on the magnetic flux.
Igor N. Karnaukhov
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Zero mode counting in the presence of background fluxes [PDF]
Nuclear Physics B - Proceedings Supplements, 2007 To obtain a superpotential contribution from a D3-instanton in type IIB string theory, two fermionic zero modes should be present on the worldvolume of a D3-brane wrapping a four-cycle. We discuss this criterium in the presence of fluxes for different configurations of O-planes and Euclidean D3-branes.
openaire +2 more sources
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Damping rates of p-modes by an ensemble of randomly distributed thin magnetic flux tubes [PDF]
, 2010 The magnetohydrodynamic (MHD) sausage tube waves are excited in the magnetic flux tubes by p-mode forcing. These tube waves thus carry energy away from the p-mode cavity which results in the deficit of incident p-mode energy.
Andrew Gascoyne, Rekha Jain
core +1 more source
Laughlin charge pumping from interplay of chiral Dirac and chiral Majorana modes
Physical Review ResearchLaughlin charge pumping has provided critical insights into the topological classification of individual materials, but remains largely unexplored in topological junctions.
Zhan Cao, Yang Feng, Zhi-Hai Liu, Ke He
doaj +1 more source