Results 111 to 120 of about 4,706,491 (312)
System-Level Insights into Yeast Metabolism by Thermodynamic Analysis of Elementary Flux Modes
PLoS Comput. Biol., 2012 One of the most obvious phenotypes of a cell is its metabolic activity, which is defined by the fluxes in the metabolic network. Although experimental methods to determine intracellular fluxes are well established, only a limited number of fluxes can be ...
Stefan J. Jol +4 more
semanticscholar +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Smooth flux-sheets with topological winding modes
, 2020 The inclusion of the Gaussian-curvature term in the bulk of Polyakov-Kleinert string action renders new boundary terms and conditions by Gauss-Bonnet theorem. Within a leading approximation, the eigenmodes of smooth worldsheets and the free-energy of a gas of open rigid strings appears to be altered at second order in the coupling by the topological ...
Bakry, A. +3 more
openaire +2 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Leaky and resonantly damped flux tube modes reconsidered [PDF]
, 1999 In this research note the results for the eigenfrequencies of the uniform and non-uniform magnetic flux tubes of Stenuit et al. (1998) are reconsidered.
Keppens, R. +3 more
core
Nutrition or nature: using elementary flux modes to disentangle the complex forces shaping prokaryote pan-genomes. [PDF]
BMC Ecol Evol, 2022 Garza DR +5 more
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Eigen modes of flux line lattice and the melting of Abrikosov flux lattice [PDF]
, 2009 The eigen modes of the flux line lattice (FLL) are discussed under a suitable transformation of the field operators. The non-local effective Hamiltonian governing the fluctuation of the FLL can be diagonalized.
陳惟堯; Chen, W. Y.; Chang, S. Y.
core
Excitation of the primary tropospheric chemical mode in a global three-dimensional model [PDF]
, 2000 Coupling of local chemical processes over the globe by atmospheric transport leads to the existence of chemical modes that are a fundamental characterization of global atmospheric chemistry and provide a true description of the atmospheric response to ...
Wild, Oliver +5 more
core +1 more source